Extensive epidemiological and clinical evidence associates diets high in flavanol-containing
foods with cardiovascular health benefits in humans. Catechin and epicatechin, the most …

Abstract Flavanols, or flavan-3-ols, are a family of bioactive compounds present in cocoa,
red wine, green tea, red grapes, berries and apples. With a basic monomer unit of (−) …

Accumulating evidence suggests that foods rich in flavanols decrease the risk of developing
cardiovascular diseases. Attenuation of oxidative stress was suggested to contribute to the …

Diet is a major lifestyle factor in the primary and secondary prevention of numerous chronic
diseases, including myocardial infarction, stroke, and diabetes. Epidemiological studies …

Scope Dietary flavanols produce beneficial health effects, and once absorbed, they are
recognized as xenobiotics and undergo phase‐II enzymatic detoxification. Flavanols health …

After absorption in the gastrointestinal tract,(−)-epicatechin is extensively transformed into
various conjugated metabolites. These metabolites, chemically different from the aglycone …

Flavanols and their related oligomeric compounds, the procyanidins, have received
increased attention during the past decade due to their reported health benefits. On the …

An increasing body of epidemiologic evidence supports the concept that diets rich in fruits
and vegetables can promote health and attenuate, or delay, the onset of various diseases …

Background: Accumulating data show a causal role for flavanols in the mediation of
cardiovascular benefits associated with the consumption of flavanol-and procyanidin …

A large body of evidence supports that the dietary intake of polyphenols-particularly of
flavonoids and the specific class of flavonoids named flavanols-might be able to exert some …