The role of natural products and their multitargeted approach to treat solid cancer

N Muhammad, D Usmani, M Tarique, H Naz, M Ashraf… - Cells, 2022 - mdpi.com
Natural products play a critical role in the discovery and development of numerous drugs for
the treatment of various types of cancer. These phytochemicals have demonstrated anti …

[HTML][HTML] Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents

S Hashem, TA Ali, S Akhtar, S Nisar, G Sageena… - Biomedicine & …, 2022 - Elsevier
Cancer is one of the leading causes of death and significantly burdens the healthcare
system. Due to its prevalence, there is undoubtedly an unmet need to discover novel …

Natural products: An upcoming therapeutic approach to cancer

S Dutta, S Mahalanobish, S Saha, S Ghosh… - Food and Chemical …, 2019 - Elsevier
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …

Natural products in cancer therapy: Past, present and future

M Huang, JJ Lu, J Ding - Natural products and bioprospecting, 2021 - Springer
Natural products, with remarkable chemical diversity, have been extensively investigated for
their anticancer potential for more than a half-century. The collective efforts of the community …

Plant natural products: from traditional compounds to new emerging drugs in cancer therapy

L Ouyang, Y Luo, M Tian, SY Zhang, R Lu… - Cell …, 2014 - Wiley Online Library
Natural products are chemical compounds or substances produced naturally by living
organisms. With the development of modern technology, more and more plant extracts have …

Exploring the recent trends in perturbing the cellular signaling pathways in cancer by natural products

MM Rahman, MT Sarker, MA Alam Tumpa… - Frontiers in …, 2022 - frontiersin.org
Cancer is commonly thought to be the product of irregular cell division. According to the
World Health Organization (WHO), cancer is the major cause of death globally. Nature offers …

Natural products as potential cancer therapy enhancers: A preclinical update

A Agbarya, N Ruimi, R Epelbaum… - SAGE open …, 2014 - journals.sagepub.com
Cancer is a multifactorial disease that arises as a consequence of alterations in many
physiological processes. Recently, hallmarks of cancer were suggested that include …

Back to basics: how natural products can provide the basis for new therapeutics

A Deorukhkar, S Krishnan, G Sethi… - Expert opinion on …, 2007 - Taylor & Francis
Phytochemicals have potent antitumor properties and have provided multiple active
compounds in the past. Although there is an increasing focus on 'designer'targeted …

Medicinal plants and bioactive natural compounds for cancer treatment: Important advances for drug discovery

F Majolo, LKOB Delwing, DJ Marmitt… - Phytochemistry …, 2019 - Elsevier
Cancer is one of the largest causes of morbimortality in the world and due to its prevalence
the discovery of novel anticancer drugs in of great importance. The past century brought …