Cell-generated extracellular vesicles (EVs) are being engineered as biologically-inspired
vehicles for targeted delivery of therapeutic agents to treat difficult-to-manage human …

Lysosomal storage disorders (LSDs) are a vast group of more than 50 clinically identified
metabolic diseases. They are singly rare, but they affect collectively 1 on 5,000 live births …

Extracellular vesicles (EVs) have received increasing attention over the last two decades.
Initially, they were considered as just a garbage disposal tool; however, it has progressively …

Lysosomal storage disorders (LSD) are a group of rare life-threatening diseases caused by
a lysosomal dysfunction, usually due to the lack of a single enzyme required for the …

Genetic mutations that cause specific lysosomal protein deficiencies account for more than
45 Lysosomal Storage Diseases (LSDs), mostly pre-adult disorders which are associated …

Introduction: The success of the first enzyme replacement therapy (ERT) for a lysosomal
storage disease (LSD) and the regulatory and commercial incentives provided by authorities …

Over the past few decades, there has been a notable increase in the global burden of
central nervous system (CNS) diseases. Despite advances in technology and therapeutic …

Rapidly growing interest in the study of extracellular vesicles (EVs) has led to the
accumulation of evidence on their critical roles in various pathologies, as well as …

Extracellular vesicles (EVs) include a heterogeneous group of natural cell-derived
nanostructures that are increasingly regarded as promising biotherapeutic agents and drug …

Cells secrete extracellular vesicles (EVs) for intercellular communication. EVs are natural
nanovesicles that are surrounded by lipid bilayer for delivery of assorted cargoes for …