Major depressive disorder (MDD) is common and moderately heritable. Recurrence and early age at onset characterize cases with the greatest familial risk. Major depressive …
FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
Abstract Data from the Genetic Association Information Network (GAIN) genome-wide association study (GWAS) in major depressive disorder (MDD) were used to explore …
EC Dunn, RC Brown, Y Dai, J Rosand… - Harvard review of …, 2015 - journals.lww.com
CME Harvard Review of Psychiatry offers CME for readers who complete questions about featured articles. Questions can be accessed from the Harvard Review of Psychiatry website …
Importance Genetic studies with broad definitions of depression may not capture genetic risk specific to major depressive disorder (MDD), raising questions about how depression …
Background The genetics of depression has been explored in genome-wide association studies that focused on either major depressive disorder or depressive symptoms with …
Abstract Purpose of Review We will describe the success of recent genome-wide association studies that identify genetic variants associated with depression and outline the …
G Breen, BT Webb, AW Butler… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: The purpose of this study was to find loci for major depression via linkage analysis of a large sibling pair sample. Method: The authors conducted a genome-wide …
In a number of human diseases, including depression, interactions between genetic and environmental factors have been identified in the absence of direct genotype-disorder …
BackgroundIt has been well established that both genes and non-shared environment contribute substantially to the underlying aetiology of major depressive disorder (MDD). A …