[HTML][HTML] Uncovering the potential role of oxidative stress in the development of periodontitis and establishing a stable diagnostic model via combining single-cell and …
G Song, G Peng, J Zhang, B Song, J Yang… - Frontiers in …, 2023 - frontiersin.org
Background The primary pathogenic cause of tooth loss in adults is periodontitis, although
few reliable diagnostic methods are available in the early stages. One pathological factor …
few reliable diagnostic methods are available in the early stages. One pathological factor …
[HTML][HTML] Deep learning reveals key immunosuppression genes and distinct immunotypes in periodontitis
W Ning, A Acharya, Z Sun, AC Ogbuehi, C Li… - Frontiers in …, 2021 - frontiersin.org
Background Periodontitis is a chronic immuno-inflammatory disease characterized by
inflammatory destruction of tooth-supporting tissues. Its pathogenesis involves a …
inflammatory destruction of tooth-supporting tissues. Its pathogenesis involves a …
[HTML][HTML] Exploring the imbalance of periodontitis immune system from the cellular to molecular level
L He, L Liu, T Li, D Zhuang, J Dai, B Wang, L Bi - Frontiers in Genetics, 2021 - frontiersin.org
Periodontitis is a common chronic inflammatory disease of periodontal tissue, mostly
concentrated in people over 30 years old. Statistics show that compared with foreign …
concentrated in people over 30 years old. Statistics show that compared with foreign …
[HTML][HTML] Investigation of molecular biomarker candidates for diagnosis and prognosis of chronic periodontitis by bioinformatics analysis of pooled microarray gene …
A Suzuki, T Horie, Y Numabe - BMC Oral Health, 2019 - Springer
Background Chronic periodontitis (CP) is a multifactorial inflammatory disease. For the
diagnosis of CP, it is necessary to investigate molecular biomarkers and the biological …
diagnosis of CP, it is necessary to investigate molecular biomarkers and the biological …
[HTML][HTML] Expression profiling and cell type classification analysis in periodontitis reveal dysregulation of multiple lncRNAs in plasma cells
D Wu, P Zhou, F Cao, Z Lin, D Liang, X Zhou - Frontiers in genetics, 2020 - frontiersin.org
Objective Periodontitis is a chronic inflammatory disease with a downregulated immune
response. The mechanisms of the immune response, especially regarding immune-related …
response. The mechanisms of the immune response, especially regarding immune-related …
Exploration of the shared gene signatures and molecular mechanisms between periodontitis and inflammatory bowel disease: evidence from transcriptome data
C Zhan, Z Zhou, Y Huang, S Huang, Z Lin… - Gastroenterology …, 2023 - academic.oup.com
Background Periodontitis disease (PD) is associated with a systemic disorder of
inflammatory bowel disease (IBD). The immune response is the common feature of the two …
inflammatory bowel disease (IBD). The immune response is the common feature of the two …
Identification of key genes and pathways associated with oxidative stress in periodontitis
Z Zhang, Y Zheng, X Bian, M Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
Background and Objective. Oxidative stress has been associated with the progression of
periodontitis. However, oxidative stress‐related genes (OS‐genes) have not been used as …
periodontitis. However, oxidative stress‐related genes (OS‐genes) have not been used as …
[HTML][HTML] Identification and validation of a classifier based on hub aging-related genes and aging subtypes correlation with immune microenvironment for periodontitis
L Peng, H Chen, Z Wang, Y He, X Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Background Periodontitis (PD), an age-related disease, is characterized by inflammatory
periodontal tissue loss, and with the general aging of the global population, the burden of …
periodontal tissue loss, and with the general aging of the global population, the burden of …
[HTML][HTML] Single-cell RNA sequencing reveals rebalancing of immunological response in patients with periodontitis after non-surgical periodontal therapy
Background Periodontitis is a major inflammatory disease of the oral mucosa that is not
limited to the oral cavity but also has systemic consequences. Although the importance of …
limited to the oral cavity but also has systemic consequences. Although the importance of …
[HTML][HTML] Single-cell RNA sequencing identifies new inflammation-promoting cell subsets in Asian patients with chronic periodontitis
S Qian, Q Huang, R Chen, J Mo, L Zhou… - Frontiers in …, 2021 - frontiersin.org
Periodontitis is a highly prevalent chronic inflammatory disease leading to periodontal tissue
breakdown and subsequent tooth loss, in which excessive host immune response accounts …
breakdown and subsequent tooth loss, in which excessive host immune response accounts …