Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients …

ZM Chen… - European Journal of …, 2000 - academic.oup.com
Assessing combined anti-platelet therapy in suspected acute myocardial infarction Aspirin
has been shown to be effective in the emergency treatment of acute myocardial infarction. It …

Addition of clopidogrel to aspirin in 45 852 patients with acute myocardial infarction: randomised placebo-controlled trial

COMMIT (ClOpidogrel and Metoprolol in Myocardial … - The Lancet, 2005 - thelancet.com
Background Despite improvements in the emergency treatment of myocardial infarction (MI),
early mortality and morbidity remain high. The antiplatelet agent clopidogrel adds to the …

Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable …

RJG Peters, SR Mehta, KAA Fox, F Zhao, BS Lewis… - Circulation, 2003 - Am Heart Assoc
Background—We studied the benefits and risks of adding clopidogrel to different doses of
aspirin in the treatment of patients with acute coronary syndrome (ACS). Methods and …

Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy

K Moshfegh, M Redondo, F Julmy… - Journal of the American …, 2000 - jacc.org
OBJECTIVES We sought to compare the inhibitory effects of the combination of two doses of
aspirin plus clopidogrel with either drug alone on platelet aggregation and activation …

Meta-analysis of the efficacy and safety of clopidogrel plus aspirin as compared to antiplatelet monotherapy for the prevention of vascular events

ADK Bowry, MA Brookhart, NK Choudhry - The American journal of …, 2008 - Elsevier
Antiplatelet agents are central to the treatment and prevention of cardiovascular disease.
Although aspirin is the most widely used agent, randomized trials have assessed whether …

[HTML][HTML] A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C‐reactive protein following myocardial infarction: the CADET …

M Woodward, GDO Lowe, LMA Francis… - Journal of Thrombosis …, 2004 - Elsevier
A randomized, double‐blind multicenter trial—the Clopidogrel and Aspirin: Determination of
the Effects on Thrombogenicity (CADET) trial—was carried out to compare the effects of …

Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study

SR Mehta, S Yusuf, RJG Peters, ME Bertrand… - The Lancet, 2001 - thelancet.com
Background Despite the use of aspirin, there is still a risk of ischaemic events after
percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to …

Dose comparisons of clopidogrel and aspirin in acute coronary syndromes

Current–Oasis 7 Investigators - New England Journal of Medicine, 2010 - Mass Medical Soc
Background Clopidogrel and aspirin are widely used for patients with acute coronary
syndromes and those undergoing percutaneous coronary intervention (PCI). However …

[HTML][HTML] Aspirin combined with clopidogrel (Plavix) decreases cardiovascular events in patients with acute coronary syndrome

CW Walker, CA Dawley, SF Fletcher - American Family Physician, 2007 - aafp.org
A combination of aspirin and clopidogrel decreased cardiovascular events in patients at
high risk of cardiovascular disease and in those with acute coronary syndrome. However …

Aspirin and clopidogrel in acute coronary syndromes: therapeutic insights from the CURE study

H Jneid, DL Bhatt, R Corti, JJ Badimon… - Archives of internal …, 2003 - jamanetwork.com
Platelet adhesion, activation, and aggregation are central to thrombus formation, which
follows atherosclerotic plaque disruption and causes acute coronary syndromes. Aspirin and …