[HTML][HTML] Comparison of COVID-19 characteristics in Egyptian patients according to their Toll-Like Receptor-4 (Asp299Gly) polymorphism

SI Taha, AK Shata, EM El-Sehsah… - Le Infezioni in …, 2022 - ncbi.nlm.nih.gov
Background Toll-like receptor (TLR)-4 plays a vital role in recognizing viral particles,
activating the innate immune system, and producing pro-inflammatory cytokines. Objectives …

Toll-like receptor 4 polymorphisms (896A/G and 1196C/T) as an indicator of COVID-19 severity in a convenience sample of Egyptian patients

SI Taha, AK Shata, SA Baioumy, SH Fouad… - Journal of …, 2021 - Taylor & Francis
Background The clinical spectrum of COVID-19 is extremely variable. Thus, it is likely that
the heterogeneity in the genetic make-up of the host may contribute to disease severity. Toll …

The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19

G Bagci, O Gundogdu, AN Pektas, B Bagci… - … Nucleotides & Nucleic …, 2023 - Taylor & Francis
Toll-like receptors (TLRs) recognize infectious agents and play an important role in the
innate immune system. Studies have suggested that TLR single nucleotide polymorphisms …

Prognostic impact of toll-like receptors gene polymorphism on outcome of COVID-19 pneumonia: A case-control study

MM Alseoudy, M Elgamal, DA Abdelghany, AM Borg… - Clinical …, 2022 - Elsevier
Abstract Toll-like receptor 3 (TLR3) and TLR7 genes are involved in the host immune
response against viral infections including SARS-COV-2. This study aimed to investigate the …

[HTML][HTML] Variant rs4986790 of toll-like receptor 4 affects the signaling and induces cell dysfunction in patients with severe COVID-19

J Flores-Gonzalez, L Chavez-Galan… - International Journal of …, 2024 - Elsevier
Objectives We investigated the expression of toll-like receptor (TLR)-4 on the cell surface of
innate and adaptive cells from patients with COVID-19 carrying the rs4986790 GG genotype …

[HTML][HTML] Effect of toll-like receptor 7 gene polymorphism and ABO blood groups on the severity of COVID-19 patients

ZHD Al-Tamimi, AH Alta'ee, AH Jasim - Acta Informatica Medica, 2022 - ncbi.nlm.nih.gov
Background: The most current threat to global health is the continuous spread of a
respiratory disease known as COVID-19 Disease 2019 in recent years. COVID-19 was …

COVID-19 susceptibility, severity, clinical outcome and Toll-like receptor (7) mRNA expression driven by TLR7 gene polymorphism (rs3853839) in middle-aged …

SM El-Hefnawy, HA Eid, RG Mostafa, SS Soliman… - Gene Reports, 2022 - Elsevier
Background Toll-like receptors are implicated in the pathophysiology of the severe acute
respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory disease …

Impact of toll-like receptor 2 and 9 gene polymorphisms on COVID-19: susceptibility, severity, and thrombosis

AM Alhabibi, AS Hassan, NM Abd Elbaky… - Journal of …, 2023 - Taylor & Francis
Background Toll-like receptors (TLRs) play an important role in activation of innate and
adaptive immune responses. Aim We aimed to detect the association between TLR2 …

No Association between SARS-CoV-2 Infection and the Polymorphism of the Toll-like Receptor 7 (TLR7) Gene in Female Population

M Zayed, YC Kim, CS Lee, BH Jeong - Diagnostics, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), a single-stranded RNA virus. Toll-like receptor 7 (TLR7) …

[HTML][HTML] TLR8 is highly conserved among the Saudi population and its mutations have no effect on the severity of COVID-19 symptoms

WH Mahallawi, BA Suliman - American Journal of Clinical and …, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus 2019 (COVID-19) is an infection caused by the newly discovered
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The innate system is the …