Vascular inflammation and the renin-angiotensin system

AR Brasier, A Recinos III, MS Eledrisi - … , thrombosis, and vascular …, 2002 - Am Heart Assoc
It is now well established that vascular inflammation is an independent risk factor for the
development of atherosclerosis. In otherwise healthy patients, chronic elevations of …

Inflammation may be a bridge connecting hypertension and atherosclerosis

JJ Li, JL Chen - Medical hypotheses, 2005 - Elsevier
Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized
by chronic inflammatory response. Although hypertension is known to be one of the most …

The renin‐angiotensin system modulates inflammatory processes in atherosclerosis: evidence from basic research and clinical studies

F Montecucco, A Pende, F Mach - Mediators of inflammation, 2009 - Wiley Online Library
Recent evidence shows that the renin‐angiotensin system is a crucial player in
atherosclerotic processes. The regulation of arterial blood pressure was considered from its …

The regulation of the inflammatory response through nuclear factor-κB pathway by angiotensin IV extends the role of the renin angiotensin system in cardiovascular …

M Ruiz-Ortega, V Esteban, J Egido - Trends in cardiovascular medicine, 2007 - Elsevier
The renin angiotensin system (RAS) participates in the pathogenesis of cardiovascular
diseases. Although angiotensin II has been considered the effector peptide of RAS …

Angiotensin induces inflammatory activation of human vascular smooth muscle cells

R Kranzhöfer, J Schmidt, CAH Pfeiffer… - … , and vascular biology, 1999 - Am Heart Assoc
Multiple data suggest that the renin-angiotensin system contributes to the pathogenesis of
atherosclerosis. The atherogenic effect of the renin-angiotensin system can only in part be …

Inflammation and angiotensin II

Y Suzuki, M Ruiz-Ortega, O Lorenzo, M Ruperez… - The international journal …, 2003 - Elsevier
Angiotensin II (AngII), the major effector peptide of renin–angiotensin system (RAS), is now
recognized as a growth factor that regulates cell growth and fibrosis, besides being a …

Role of the renin–angiotensin system in vascular inflammation

C Marchesi, P Paradis, EL Schiffrin - Trends in pharmacological sciences, 2008 - cell.com
Angiotensin (Ang) II, the main effector of the renin–angiotensin system (RAS), is one of the
major mediators of vascular remodeling in hypertension. Besides being a potent vasoactive …

Inflammation as a regulator of the renin-angiotensin system and blood pressure

R Satou, H Penrose, LG Navar - Current hypertension reports, 2018 - Springer
Abstract Purpose of Review Mechanisms facilitating progression of hypertension via cross
stimulation of the renin-angiotensin system (RAS) and inflammation have been proposed …

[PDF][PDF] Angiotensin II and vascular inflammation

ZJ Cheng, H Vapaatalo, E Mervaala - Med Sci Monit, 2005 - researchgate.net
Vascular inflammation is involved in the initiation and progression of atherosclerosis, and is
also present in hypertension-and diabetes-induced vascular complications. Angiotensin II …

Angiotensin II and inflammation: the effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade

P Dandona, S Dhindsa, H Ghanim… - Journal of human …, 2007 - nature.com
Abstract Angiotensin II (Ang II) increases adhesion molecules, cytokines and chemokines
and exerts a proinflammatory effect on leucocytes, endothelial cells and vascular smooth …