The severity of coronavirus disease 2019 (COVID‐19) is a crucial problem in patient
treatment and outcome. The aim of this study is to evaluate circulating level of sphingosine …

The recent coronavirus disease (COVID-19) is still spreading worldwide. The severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), the virus responsible for COVID-19 …

The reason behind the high inter-individual variability in response to SARS-CoV-2 infection
and patient's outcome is poorly understood. The present study targets the sphingolipid …

Summary Background: The sphingolipid sphingosine-1-phosphate (S1P) plays an important
role in protecting the heart against ischemia-reperfusion injury. S1P is normally present in …

Understanding pathways that might impact coronavirus disease 2019 (COVID-19)
manifestations and disease outcomes is necessary for better disease management and for …

Sepsis is an acute life-threatening multiple organ failure caused by a dysregulated host
response to infection. Endothelial dysfunction, particularly barrier disruption leading to …

COVID-19 pandemic exerts a health care emergency around the world. The illness severity
is heterogeneous. It is mostly unknown why some individuals who are positive for SARS …

Abstract Objective Sphingosine-1-Phosphate (S1P) is a bioactive sphingolipid with
important functions in immunity, inflammation and cardiovascular biology. S1P is associated …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic with severe consequences for afflicted individuals and the society as a whole …

Abstract Sphingosine-1-phosphate (S1P) is a signaling lipid, synthetized by sphingosine
kinases (SPHK1 and SPHK2), that affects cardiovascular function in various ways. S1P …