UpPipe: A Novel Pipeline Management on In-Memory Processors for RNA-seq Quantification

LC Chen, CC Ho, YH Chang - 2023 60th ACM/IEEE Design …, 2023 - ieeexplore.ieee.org
RNA sequence quantification is an important analysis method to measure transcript
abundances. A key overhead in RNA-seq quantification is to map a set of RNA reads to …

RNA-seq Quantification on Processing in memory Architecture: Observation and Characterization

LC Chen, SQ Yu, CC Ho, YH Chang… - 2022 IEEE 11th Non …, 2022 - ieeexplore.ieee.org
In recent years, the processing in memory (PIM) technique has progressively captured
people's attention since it reveals the potential to strike down the von Neumann bottleneck …

aRNApipe: a balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environments

A Alonso, BN Lasseigne, K Williams, J Nielsen… - …, 2017 - academic.oup.com
The wide range of RNA-seq applications and their high-computational needs require the
development of pipelines orchestrating the entire workflow and optimizing usage of …

Accelerated genomics data processing using memory-driven computing

M Becker, M Chabbi… - 2019 IEEE …, 2019 - ieeexplore.ieee.org
Next generation sequencing (NGS) is the driving force behind precision medicine and is
revolutionizing most, if not all, areas of the life sciences. Particularly when targeting the …

Holistic optimization of an RNA-seq workflow for multi-threaded environments

LH Hung, W Lloyd, R Agumbe Sridhar… - …, 2019 - academic.oup.com
For many next generation-sequencing pipelines, the most computationally intensive step is
the alignment of reads to a reference sequence. As a result, alignment software such as the …

Pim-quantifier: A processing-in-memory platform for mrna quantification

F Zhang, S Angizi, NA Fahmi… - 2021 58th ACM/IEEE …, 2021 - ieeexplore.ieee.org
Processing-in-memory (PIM) architecture has been considered as a promising solution for
the “memory-wall” issue in many data-intensive applications, especially in bioinformatics …

Beacon: Scalable near-data-processing accelerators for genome analysis near memory pool with the cxl support

W Huangfu, KT Malladi, A Chang… - 2022 55th IEEE/ACM …, 2022 - ieeexplore.ieee.org
Genome analysis benefits precise medical care, wildlife conservation, pandemic treatment
(eg, COVID-19), and so on. Unfortunately, in genome analysis, the speed of data processing …

Cram-seq: Accelerating rna-seq abundance quantification using computational ram

ZI Chowdhury, SK Khatamifard, S Resch… - … on Emerging Topics …, 2022 - ieeexplore.ieee.org
RNA Sequence (RNA-Seq) abundance quantification is an important application in different
fields of genomic studies, eg, analysis offunctionally similar genes in a biological sample …

Memory-driven computing accelerates genomic data processing

M Becker, M Chabbi, S Warnat-Herresthal, K Klee… - bioRxiv, 2019 - biorxiv.org
Next generation sequencing (NGS) is the driving force behind precision medicine and is
revolutionizing most, if not all, areas of the life sciences. Particularly when targeting the …

A flexible automated pipeline engine for transcript-level quantification from rna-seq

P Cinaglia, M Cannataro - International Conference on Conceptual …, 2022 - Springer
The advances in massive parallel sequencing technologies (ie, Next-Generation
Sequencing) allowed RNA sequencing (RNA-seq). The analysis of RNA-seq data uses a …