Background We used a polygenic score for externalizing behavior (extPGS) and structural
MRI to examine potential pathways from genetic liability to conduct problems via the brain …

Introduction Externalizing behaviors are defined as behaviors violating social norms and
can be harmful to self and others. Predicting the escalation of externalizing behaviors in …

Objective Genetic factors contribute to individual differences in behavior problems. In
children, genome-wide association studies (GWAS) have yielded the first suggestive results …

Background Evidence that different neuropsychiatric conditions share genetic liability has
increased interest in phenotypes with 'cross‐disorder'relevance, as they may contribute to …

Objective Symptoms of psychopathology covary across diagnostic boundaries, and a family
history of elevated symptoms for a single psychiatric disorder places an individual at …

Background Childhood psychotic-like experiences (PLEs) often precede the development of
later severe psychopathology. This study examined whether childhood PLEs are associated …

Background Low and middle-income countries like India with a large youth population
experience a different environment from that of high-income countries. The Consortium on …

Objective This study examined the relation between polygenic scores (PGSs) for 5 major
psychiatric disorders and 2 cognitive traits with brain magnetic resonance imaging …

BackgroundQuestions remain regarding whether genetic influences on early life
psychopathology overlap with cognition and show developmental variation. MethodsUsing …

Etiologic insights into psychopathology may be gained by using hypothesis-free methods to
identify associations between genetic risk for broad psychopathology and phenotypes …