125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts
Q Jin, C Lin, X Zhu, Y Cao, C Guo, L Wang - Radiation Oncology, 2020 - Springer
Background Lung cancer is a fatal disease and a serious health problem worldwide.
Patients are usually diagnosed at an advanced stage, and the effectiveness of …
Patients are usually diagnosed at an advanced stage, and the effectiveness of …
125I seed irradiation induces apoptosis and inhibits angiogenesis by decreasing HIF-1α and VEGF expression in lung carcinoma xenografts
GL Xiang, XH Zhu, CZ Lin, LJ Wang… - Oncology …, 2017 - spandidos-publications.com
The purpose of this study was to examine the effects of irradiation by 125I seeds in human
lung cancer xenograft model and to determine the underlying mechanisms involved, with a …
lung cancer xenograft model and to determine the underlying mechanisms involved, with a …
Effects of I-125 seeds combined with anlotinib on tumor growth and bone metabolism in A549 tumor-bearing mice
F He, Q Bao, J Bai, J Wang, J Zhai, Q Yu… - … journal of radiation …, 2021 - Taylor & Francis
Purpose This study aimed to investigate the therapeutic potential of tumor suppression and
mechanism for different implantation modes of iodine-125 (I-125) seeds irradiation in a mice …
mechanism for different implantation modes of iodine-125 (I-125) seeds irradiation in a mice …
125I Seed Promotes Apoptosis in Non-small Lung Cancer Cells via the p38 MAPK-MDM2-p53 Signaling Pathway
T Zhang, ZQ Mo, G Duan, R Tang, F Zhang… - Frontiers in …, 2021 - frontiersin.org
Purpose: 125I seeds were effective in the treatment of non-small cell lung cancer in previous
research. However, the exact signaling pathway-mediated apoptosis mechanism is still …
research. However, the exact signaling pathway-mediated apoptosis mechanism is still …
The Effects of 12C6+ Irradiation on Cell Cycle, Apoptosis, and Expression of Caspase-3 in the Human Lung Cancer Cell Line H1299
H Xu, L Gao, T Che, W Du, Q Li, Q Gao… - Cancer Biotherapy and …, 2012 - liebertpub.com
Introduction: We aimed to investigate the effects of 12C6+ irradiation on the cell cycle and
apoptosis as well as the associated mechanisms in the human lung cancer cell line H1299 …
apoptosis as well as the associated mechanisms in the human lung cancer cell line H1299 …
A Comparison of the Biological Effects of 125I Seeds Continuous Low-Dose-Rate Radiation and 60Co High-Dose-Rate Gamma Radiation on Non-Small Cell Lung …
Z Wang, Z Zhao, J Lu, Z Chen, A Mao, G Teng, F Liu - PLoS One, 2015 - journals.plos.org
Objectives To compare the biological effects of 125I seeds continuous low-dose-rate
(CLDR) radiation and 60Co γ-ray high-dose-rate (HDR) radiation on non-small cell lung …
(CLDR) radiation and 60Co γ-ray high-dose-rate (HDR) radiation on non-small cell lung …
Continuous low-dose irradiation by I-125 seeds induces apoptosis of gastric cancer cells regardless of histological origin
K Takabayashi, K Kashiwagi, T Kawata… - Cancer biology & …, 2014 - Taylor & Francis
The efficacy of conventional radiation therapy for gastric cancer is controversial. In this study,
we evaluated the in vitro and in vivo effects of continuous low-dose-rate irradiation by I-125 …
we evaluated the in vitro and in vivo effects of continuous low-dose-rate irradiation by I-125 …
Biological Effects of 125I Seeds Radiation on A549 Lung Cancer Cells: G2/M Arrest and Enhanced Cell Death
A Qu, H Wang, J Li, J Wang, J Liu, Y Hou… - Cancer …, 2014 - Taylor & Francis
External beam radiation (EBRT) and 125I seeds continuous low dose rate radiation (CLDR)
were used to treat patients with lung cancer. We herein investigated the biological effects of …
were used to treat patients with lung cancer. We herein investigated the biological effects of …
Radioactive 125I seeds inhibit cell growth and epithelial-mesenchymal transition in human glioblastoma multiforme via a ROS-mediated signaling pathway
Y Tian, Q Xie, J He, X Luo, T Zhou, Y Liu, Z Huang… - BMC cancer, 2015 - Springer
Background Glioblastoma multiforme (GBM) is the most common primary central nervous
system neoplasm in adults. Radioactive 125 I seed implantation has been widely applied in …
system neoplasm in adults. Radioactive 125 I seed implantation has been widely applied in …
125I seed irradiation induces up-regulation of the genes associated with apoptosis and cell cycle arrest and inhibits growth of gastric cancer xenografts
ZH Ma, Y Yang, L Zou, KY Luo - Journal of Experimental & Clinical Cancer …, 2012 - Springer
Abstract Background Iodine 125 (125I) seed irradiation can be used as an important
supplementary treatment for unresectable advanced gastric cancer. Here, we aim to …
supplementary treatment for unresectable advanced gastric cancer. Here, we aim to …