Severe acute pancreatitis (SAP) is an inflammatory disease of the pancreas accompanied
by tissue injury and necrosis. It not only affects the pancreas but also triggers a systemic …

Insulin resistance (IR) is one of the essential conditions in the development of type 2
diabetes mellitus (T2DM). IR occurs in hepatic cells when the insulin receptor substrate-1 …

Sepsis has affected millions of people worldwide with high mortality rate and lack of effective
strategies. Previous studies have reported that quercetin (Que) can attenuate …

A failure in immune tolerance leads to autoimmune destruction of insulin-producing β-cells,
leading to type 1 diabetes (T1D). Inhibiting autoreactive T cells and inducing regulatory T …

Osteoarthritis (OA) is a degenerative articular cartilage pathogenic process that is
accompanied by excessive chondrocyte apoptosis. The occurrence of chondrocyte death …

Obesity-induced insulin resistance is the hallmark of metabolic syndrome, and chronic, low-
grade tissue inflammation links obesity to insulin resistance through the activation of tissue …

Antioxidants play an early intervention role in the pathogenesis of kidney injury by
alleviating oxidative damage to the injured kidney. The development of safe and effective …

While the skin is considered the first line of defense in the human body, there are some
vulnerabilities that render it susceptible to certain threats, which is an issue that is …

Retinal ischemia-reperfusion (I/R) injuries are involved in the universal pathological
processes of many ophthalmic diseases, including glaucoma, diabetic retinopathy, and …

Immunogenic cell death (ICD) is a form of programmed cell death with a strong sense of
inflammatory detection, whose powerful situational awareness can cause the reactivation of …