Wnt signaling is required for neurogenesis, the fate of neural progenitors, the formation of
neuronal circuits during development, neuron positioning and polarization, axon and …

The canonical Wnt signaling pathway is critical for development of the mammalian central
nervous system and regulates diverse processes throughout adulthood, including adult …

Parkinson's disease (PD) is one of the major neurodegenerative diseases (ND) which
presents a progressive neurodegeneration characterized by loss of dopamine in the …

Since its discovery, Wnt signaling has been shown to be one of the most crucial
morphogens in development and during the maturation of central nervous system. Its action …

Lithium has been used in modern psychiatry for more than 65 years, constituting a
cornerstone for the long-term treatment of bipolar disorder. A number of biological properties …

In the past several years, we postulated that the loss of Wnt signaling was implicated in the
pathology of Alzheimer's disease (AD). Since then, our lab and other groups have confirmed …

The Wnt/β-catenin or Wnt canonical pathway controls multiple biological processes
throughout development and adult life. Growing evidences have suggested that …

Background/Aims: The Wnt signaling pathway has essential functions in the central nervous
system, where it regulates the major physiological functions of neurons, including …

The Wnt signaling pathway has been recognized as an important pathway, extending its
function throughout the lifespan. Evidence suggests that dysfunctional Wnt signaling in the …

The Wnt pathway is the most important cascade in the nervous system; evidence has
indicated that deregulation of the Wnt pathway induced pathogenic hallmarks of …