SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact

M Lipsitch, F Krammer, G Regev-Yochay… - Nature Reviews …, 2022 - nature.com
Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …

Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveals limited infectious virus shedding and restricted tissue distribution

R Ke, PP Martinez, RL Smith, LL Gibson… - Open Forum …, 2022 - academic.oup.com
Background The global effort to vaccinate people against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) during an ongoing pandemic has raised questions about how …

Are COVID-19 vaccine boosters needed? The science behind boosters

RM Burckhardt, JJ Dennehy, LLM Poon, LJ Saif… - Journal of …, 2022 - Am Soc Microbiol
Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants
has led to increases in breakthrough infections, prompting consideration for vaccine booster …

Transmission and infectious SARS-CoV-2 shedding kinetics in vaccinated and unvaccinated individuals

J Jung, JY Kim, H Park, S Park, JS Lim… - JAMA network …, 2022 - jamanetwork.com
Importance Data are limited on whether patients with breakthrough COVID-19 infection have
the potential to significantly contribute to the spread of SARS-CoV-2. Objective To compare …

Predominance of antibody-resistant SARS-CoV-2 variants in vaccine breakthrough cases from the San Francisco Bay Area, California

V Servellita, MK Morris, A Sotomayor-Gonzalez… - Nature …, 2022 - nature.com
Associations between vaccine breakthrough cases and infection by different SARS
coronavirus 2 (SARS-CoV-2) variants have remained largely unexplored. Here we analysed …

Levels of SARS-CoV-2 antibodies among fully vaccinated individuals with Delta or Omicron variant breakthrough infections

NB Stærke, J Reekie, H Nielsen, T Benfield… - Nature …, 2022 - nature.com
SARS-CoV-2 variants of concern have continuously evolved and may erode vaccine
induced immunity. In this observational cohort study, we determine the risk of breakthrough …

Identifying and alleviating bias due to differential depletion of susceptible people in postmarketing evaluations of COVID-19 vaccines

R Kahn, SJ Schrag, JR Verani… - American journal of …, 2022 - academic.oup.com
Recent studies have provided key information about SARS-CoV-2 vaccines' efficacy and
effectiveness (VE). One important question that remains is whether the protection conferred …

Relative infectiousness of SARS-CoV-2 vaccine breakthrough infections, reinfections, and primary infections

LJ Abu-Raddad, H Chemaitelly, HH Ayoub… - Nature …, 2022 - nature.com
SARS-CoV-2 breakthrough infections in vaccinated individuals and in those who had a prior
infection have been observed globally, but the transmission potential of these infections is …

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

CM Saad-Roy, SE Morris, CJE Metcalf, MJ Mina… - Science, 2021 - science.org
INTRODUCTION As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic continues, the deployment of safe and effective vaccines presents a key …

COVID-19 vaccine waning and effectiveness and side-effects of boosters: a prospective community study from the ZOE COVID Study

C Menni, A May, L Polidori, P Louca, J Wolf… - The Lancet Infectious …, 2022 - thelancet.com
Background With the surge of new SARS-CoV-2 variants, countries have begun offering
COVID-19 vaccine booster doses to high-risk groups and, more recently, to the adult …