Differences of the immune cell landscape between normal and tumor tissue in human prostate

E Zhang, F Dai, Y Mao, W He, F Liu, W Ma… - Clinical and Translational …, 2020 - Springer
Background Over the past few decades, immunological checkpoint therapy has been an
increasingly prominent strategy in the treatment of tumors, including prostate cancer (PC) …

Understanding the tumor-immune microenvironment in prostate cancer

L Dong, KV Myers, KJ Pienta - Current opinion in oncology, 2021 - journals.lww.com
Understanding the tumor-immune microenvironment in prostate... : Current Opinion in
Oncology Understanding the tumor-immune microenvironment in prostate cancer : Current …

[HTML][HTML] Immune mediators in the tumor microenvironment of prostate cancer

J Dai, Y Lu, H Roca, JM Keller, J Zhang… - Chinese journal of …, 2017 - Springer
Prostate cancer tissue is composed of both cancer cells and host cells. The milieu of host
components that compose the tumor is termed the tumor microenvironment (TME). Host cells …

[HTML][HTML] Mass cytometry reveals species-specific differences and a new level of complexity for immune cells in the prostate

JJ Fox, HI Navarro, T Hashimoto, AJ Garcia… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Chronic inflammation in the benign prostate has been associated with a higher risk of
developing prostate cancer. While a range of immune lineages is found in the prostate …

Identification of immune-based prostate cancer subtypes using mRNA expression

J Song, W Wang, Y Yuan, Y Ban, J Su… - Bioscience …, 2021 - portlandpress.com
Abstract Immune infiltration in Prostate Cancer (PCa) was reported to be strongly associated
with clinical outcomes. However, previous research could not elucidate the diversity of …

[HTML][HTML] The landscape of immune cells infiltrating in prostate cancer

Z Wu, H Chen, W Luo, H Zhang, G Li, F Zeng… - Frontiers in …, 2020 - frontiersin.org
Background This study was to explore the infiltration pattern of immune cells in the prostate
cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune …

[HTML][HTML] Immune infiltration and prostate cancer

A Strasner, M Karin - Frontiers in oncology, 2015 - frontiersin.org
It is becoming increasingly clear that inflammation influences prostate cancer (PCa)
development and that immune cells are among the primary drivers of this effect. This …

Immunological complexity of the prostate cancer microenvironment influences the response to immunotherapy

N Prokhnevska, DA Emerson, HT Kissick… - … Cancer: Cellular and …, 2019 - Springer
Prostate cancer is one of the most common cancers in men and a leading cause of cancer-
related death. Recent advances in the treatment of advanced prostate cancer, including the …

[HTML][HTML] The tumor immune contexture of prostate cancer

N Vitkin, S Nersesian, DR Siemens, M Koti - Frontiers in immunology, 2019 - frontiersin.org
One in seven men in North America is expected to be diagnosed with prostate cancer (PCa)
during their lifetime (,). While a wide range of treatment options including surgery, radiation …

M2 subtype tumor associated macrophages (M2-TAMs) infiltration predicts poor response rate of immune checkpoint inhibitors treatment for prostate cancer

Z JiaWei, D ChunXia, L CunDong, L Yang… - Annals of …, 2021 - Taylor & Francis
Abstract Background Prostate cancer (PCa) is poor response to the immunotherapy for its
high heterogeneity of immune microenvironment. In this study, we aim to introduce a new …