[HTML][HTML] SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing

AVW Nunn, GW Guy, W Brysch, SW Botchway… - Immunity & …, 2020 - Springer
Infection with SARs-COV-2 displays increasing fatality with age and underlying co-morbidity,
in particular, with markers of the metabolic syndrome and diabetes, which seems to be …

[HTML][HTML] SARS-CoV-2 and EBV; the cost of a second mitochondrial “whammy”?

AVW Nunn, GW Guy, SW Botchway, JD Bell - Immunity & Ageing, 2021 - Springer
We, and others, have suggested that as the SARS-CoV-2 virus may modulate mitochondrial
function, good mitochondrial reserve and health could be key in determining disease …

Age-related mitochondrial dysfunction as a key factor in COVID-19 disease

DJM Fernández-Ayala, P Navas… - Experimental gerontology, 2020 - Elsevier
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …

[HTML][HTML] Understanding long COVID; mitochondrial health and adaptation—old pathways, new problems

AVW Nunn, GW Guy, W Brysch, JD Bell - Biomedicines, 2022 - mdpi.com
Many people infected with the SARS-CoV-2 suffer long-term symptoms, such as “brain fog”,
fatigue and clotting problems. Explanations for “long COVID” include immune imbalance …

[HTML][HTML] Impact of COVID-19 on mitochondrial-based immunity in aging and age-related diseases

R Ganji, PH Reddy - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) is a deadly pandemic, immune compromised
disease with no cure. The COVID-19 is caused by acute respiratory syndrome corona virus 2 …

[HTML][HTML] Mitochondria: in the cross fire of SARS-CoV-2 and immunity

J Burtscher, G Cappellano, A Omori, T Koshiba… - IScience, 2020 - cell.com
The pathophysiology, immune reaction, and differential vulnerability of different population
groups and viral host immune system evasion strategies of severe acute respiratory …

[HTML][HTML] The central role of mitochondrial fitness on antiviral defenses: An advocacy for physical activity during the COVID-19 pandemic

J Burtscher, M Burtscher, GP Millet - Redox biology, 2021 - Elsevier
Mitochondria are central regulators of cellular metabolism, most known for their role in
energy production. They can be “enhanced” by physical activity (including exercise), which …

COVID-19: a mitochondrial perspective

P Prasun - DNA and Cell Biology, 2021 - liebertpub.com
Coronavirus disease 2019 (COVID-19) is the worst public health crisis of the century.
Although we have made tremendous progress in understanding the pathogenesis of this …

[HTML][HTML] Coronavirus (Covid-19) sepsis: revisiting mitochondrial dysfunction in pathogenesis, aging, inflammation, and mortality

S Shenoy - Inflammation research, 2020 - Springer
Background Decline in mitochondrial function occurs with aging and may increase mortality.
We discuss mitochondrial contribution to Covid-19 sepsis, specifically the complex …

[HTML][HTML] Host mitochondria: more than an organelle in SARS-CoV-2 infection

S Shoraka, AE Samarasinghe, A Ghaemi… - Frontiers in Cellular …, 2023 - frontiersin.org
Since December 2019, the world has been facing viral pandemic called COVID-19
(Coronavirus disease 2019) caused by a new beta-coronavirus named severe acute …