Acquired heterotopic ossification (HO) is a painful and debilitating disease characterized by
extraskeletal bone formation after injury. The exact pathogenesis of HO remains unknown …

Heterotopic ossification (HO) is an aberrant regenerative process with ectopic bone
induction in response to musculoskeletal trauma, in which mesenchymal stem cells (MSC) …

Put most simply, heterotopic ossification (HO) is the abnormal formation of bone at
extraskeletal sites. HO can be classified into two main subtypes, genetic and acquired …

Heterotopic ossification (HO) is a debilitating condition in which cartilage and bone forms in
soft tissues such as muscle, tendon, and ligament causing immobility. This process is …

Heterotopic ossification (HO), including hereditary and acquired HO, is the formation of
extraskeletal bone in skeletal muscle and surrounding soft tissues. Acquired HO is often …

Tissue regeneration following acute or persistent inflammation can manifest a spectrum of
phenotypes ranging from the adaptive to the pathologic. Heterotopic Ossification (HO), the …

Heterotopic ossification (HO), the abnormal formation of true marrow-containing bone within
extraskeletal soft tissues, is a serious bony disorder that may be either acquired or …

Bone remodeling depends on the spatial and temporal coupling of bone formation by
osteoblasts and bone resorption by osteoclasts; however, the molecular basis of these …

Bone formation is exquisitely controlled both spatially and temporally. Heterotopic
ossification (HO) is pathological bone formation in soft tissues that often leads to deleterious …

Heterotopic ossification (HO) is the formation of extraskeletal bone in non-osseous tissues. It
is caused by an injury that stimulates abnormal tissue healing and regeneration, and …