Primary aging is the progressive and inevitable process of bodily deterioration during
adulthood. In skeletal muscle, primary aging causes defective mitochondrial energetics and …

A substantial loss of muscle mass and strength (sarcopenia), a decreased regenerative
capacity, and a compromised physical performance are hallmarks of aging skeletal muscle …

Aging is associated with mitochondrial dysfunction, which leads to a decline in cellular
function and the development of age-related diseases. Reduced skeletal muscle mass with …

Skeletal muscle aging is associated with a decline in motor function and loss of muscle
mass-a condition known as sarcopenia. The underlying mechanisms that drive this …

Skeletal muscle health is dependent on the optimal function of its mitochondria. With
advancing age, decrements in numerous mitochondrial variables are evident in muscle. Part …

Decline in human muscle mass and strength (sarcopenia) is a hallmark of the aging
process. A growing body of research in the areas of bioenergetics and protein turnover has …

Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines
in skeletal muscle mitochondria are thought to play a primary role in this process …

Aging is inevitably associated with a progressive loss of muscle mass and strength, a
condition also known as sarcopenia of aging. Although the precise mechanisms underlying …

Mitochondria are negatively affected by ageing leading to their inability to adapt to higher
levels of oxidative stress and this ultimately contributes to the systemic loss of muscle mass …

Inactivity accelerates muscle catabolism, mitochondrial dys-function, and oxidative stress
accumulation and reduces aerobic capacity. This chapter aims to assess the role of exercise …