J Yan, G Zuo, P Sherchan, L Huang, U Ocak, W Xu… - …, 2020 - Elsevier
The activation of CC chemokine receptor type 1 (CCR1) has been shown to be pro- inflammatory in several animal models of neurological diseases. The objective of this study …
Background C–C chemokine receptor type 1 (CCR1) and its endogenous ligand, CCL5, participate in the pathogenesis of neuroinflammatory diseases. However, much remains …
S Deng, P Jin, P Sherchan, S Liu, Y Cui… - Journal of …, 2021 - Springer
Background Intracerebral hemorrhage (ICH), a devastating subtype of stroke, is associated with high mortality and morbidity. Neuroinflammation is an important factor leading to ICH …
F Guo, D Xu, Y Lin, G Wang, F Wang, Q Gao… - The FASEB …, 2020 - Wiley Online Library
Intracerebral hemorrhage (ICH) remains a devastating type of stroke that lacks an effective treatment. Recent evidence has demonstrated that CCL2 is involved in the blood‐brain …
S Zhou, C Liu, J Wang, J Ye, Q Lian… - Journal of Cerebral …, 2024 - journals.sagepub.com
The crosstalk between reactive astrocytes and infiltrated immune cells plays a critical role in maintaining blood-brain barrier (BBB) integrity. However, how astrocytes interact with …
MD Hammond, RA Taylor, MT Mullen, Y Ai… - Journal of …, 2014 - Soc Neuroscience
Intracerebral hemorrhage (ICH) is a devastating type of stroke that lacks a specific treatment. An intense immune response develops after ICH, which contributes to neuronal injury …
Intracerebral hemorrhage (ICH) has been associated with inflammation and apoptosis. The CCL2‐CCR2 chemotactic system is one of the major signaling pathways that induce …
Q Tian, Y Guo, S Feng, C Liu, P He, J Wang… - Journal of …, 2022 - Springer
Background Neuroinflammation and neuronal apoptosis are closely associated with a poor prognosis in patients with subarachnoid hemorrhage (SAH). We investigated the role of C–C …
S Deng, P Sherchan, P Jin, L Huang, Z Travis… - …, 2020 - Elsevier
Hematoma is a crucial factor leading to poor prognosis after intracerebral hemorrhage (ICH). Promoting microglial phagocytosis to enhance hematoma resolution may be an important …