Background Owing to metabolic disequilibrium and immune suppression, intracerebral
hemorrhage (ICH) patients are prone to infections; according to a recent global analysis of …

The activation of CC chemokine receptor type 1 (CCR1) has been shown to be pro-
inflammatory in several animal models of neurological diseases. The objective of this study …

Background C–C chemokine receptor type 1 (CCR1) and its endogenous ligand, CCL5,
participate in the pathogenesis of neuroinflammatory diseases. However, much remains …

Background Intracerebral hemorrhage (ICH), a devastating subtype of stroke, is associated
with high mortality and morbidity. Neuroinflammation is an important factor leading to ICH …

Intracerebral hemorrhage (ICH) remains a devastating type of stroke that lacks an effective
treatment. Recent evidence has demonstrated that CCL2 is involved in the blood‐brain …

The crosstalk between reactive astrocytes and infiltrated immune cells plays a critical role in
maintaining blood-brain barrier (BBB) integrity. However, how astrocytes interact with …

Intracerebral hemorrhage (ICH) is a devastating type of stroke that lacks a specific treatment.
An intense immune response develops after ICH, which contributes to neuronal injury …

Intracerebral hemorrhage (ICH) has been associated with inflammation and apoptosis. The
CCL2‐CCR2 chemotactic system is one of the major signaling pathways that induce …

Background Neuroinflammation and neuronal apoptosis are closely associated with a poor
prognosis in patients with subarachnoid hemorrhage (SAH). We investigated the role of C–C …

Hematoma is a crucial factor leading to poor prognosis after intracerebral hemorrhage (ICH).
Promoting microglial phagocytosis to enhance hematoma resolution may be an important …