The devastating consequences of AIDS pandemic will probably only be controlled when a
vaccine is developed that is safe, effective, affordable, and simple enough to permit …

HIV-1 genetic variability within individuals and populations plays a central role in the HIV
pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV …

HIV-1 strains have diversified extensively through mutation and recombination since their
initial transmission to human beings many decades ago in central Africa. The high error rate …

This review examines the enormous progress that has been made in the past decade in
understanding the origin of HIV, HIV genetic variability, and the impact of global HIV diversity …

Publisher Summary This chapter describes the classification and distribution of human
immunodeficiency virus (HIV) genotypes and the biological and public health implications of …

Abstract HIV type 1 (HIV-1) displays a greater degree of genetic and antigenic variability
than any other virus studied. This diversity reflects a high mutation rate during viral …

HIV molecular epidemiology: transmission and adaptation to h... : Current Opinion in HIV and
AIDS HIV molecular epidemiology: transmission and adaptation to human populations …

The human immunodeficiency virus type 1 (HIV-1) originated in non-human primates in
West-central Africa and continues to be a major global public health issue, having claimed …

Background: HIV-1 evolves by rapid mutation and by recombination, both processes actively
contributing to its genetic diversity. Most of the multiple genetic subtypes and intersubtype …

The magnitude of the HIV pandemic and its extensive genetic variation may earn it a unique
place among infectious agents. A high mutation rate and a rampant recombination are …