This article develops the iSTART neural model that proposes how specific imbalances in
cognitive, emotional, timing, and motor processes that involve brain regions like prefrontal …

Attentional deficits and executive function impairments are common to many
neurodevelopmental disorders of intellectual disability and autism, including Fragile X …

Cerebellar dysfunction has been linked to autism spectrum disorders (ASDs). Although
cerebellar pathology has been observed in individuals with fragile X syndrome (FXS) and in …

Individuals with fragile X syndrome (FXS) are frequently diagnosed with autism spectrum
disorder (ASD), including increased risk for restricted and repetitive behaviors (RRBs) …

Restricted, repetitive behaviors (RRBs) are heterogeneous ranging from stereotypic body
movements to rituals to restricted interests. RRBs are most strongly associated with autism …

Background Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased
high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to …

Fragile X (FX) is the most common genetic cause of intellectual disability and autism.
Previous studies have shown that partial inhibition of metabotropic glutamate receptor …

Fragile X syndrome (FXS), a commonly inherited form of autism and intellectual disability, is
associated with emotional symptoms that implicate dysfunction of the amygdala. However …

Abstract Fragile X Syndrome (FXS) is a monogenetic form of intellectual disability and
autism in which well-established knockout (KO) animal models point to neuronal …

Objective To investigate the neural mechanisms underlying impairments in generalizing
learning shown by adolescents with autism spectrum disorder (ASD). Method A total of 21 …