[HTML][HTML] Breast cancer cell–derived microRNA-155 suppresses tumor progression via enhancing immune cell recruitment and antitumor function
J Wang, Q Wang, Y Guan, Y Sun… - The Journal of …, 2022 - Am Soc Clin Investig
Evidence suggests that increased microRNA-155 (miR-155) expression in immune cells
enhances antitumor immune responses. However, given the reported association of miR …
enhances antitumor immune responses. However, given the reported association of miR …
MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene
Abstract MicroRNA-155 (miR-155) is overexpressed in many human cancers; however, the
mechanisms by which miR-155 functions as a putative oncomiR are largely unknown. Here …
mechanisms by which miR-155 functions as a putative oncomiR are largely unknown. Here …
[HTML][HTML] The role of miR-155 in antitumor immunity
K Kalkusova, P Taborska, D Stakheev, D Smrz - Cancers, 2022 - mdpi.com
Simple Summary MiR-155 appears to be a significant regulator of immune responses
against tumors. The aim of this review is to provide an overview of miR-155 function in …
against tumors. The aim of this review is to provide an overview of miR-155 function in …
[HTML][HTML] The multiple roles of microRNA-155 in oncogenesis
The microRNA miR-155 is prominent in cancer biology. Among microRNAs that have been
linked to cancer, it is the most commonly overexpressed in malignancies (PNAS 109: 20047 …
linked to cancer, it is the most commonly overexpressed in malignancies (PNAS 109: 20047 …
[HTML][HTML] High expression of microRNA-143 is associated with favorable tumor immune microenvironment and better survival in estrogen receptor positive breast …
microRNA-143 (miR-143) is a well-known tumor suppressive microRNA that exhibits anti-
tumoral function by targeting KRAS signaling pathways in various malignancies. We …
tumoral function by targeting KRAS signaling pathways in various malignancies. We …
[HTML][HTML] Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration
S Kim, JH Song, S Kim, P Qu, BK Martin… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The oncogenic role of microRNA-155 (miR-155) in leukemia is well established but its role
in other cancers, especially breast cancer, is gradually emerging. In this study we examined …
in other cancers, especially breast cancer, is gradually emerging. In this study we examined …
[HTML][HTML] Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade
TB Huffaker, SH Lee, WW Tang, JA Wallace… - Journal of Biological …, 2017 - ASBMB
MicroRNA-155 (miR-155) regulates antitumor immune responses. However, its specific
functions within distinct immune cell types have not been delineated in conditional KO …
functions within distinct immune cell types have not been delineated in conditional KO …
[HTML][HTML] MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers
HA Ekiz, TB Huffaker, AH Grossmann, WZ Stephens… - JCI insight, 2019 - ncbi.nlm.nih.gov
Abstract miR-155 has recently emerged as an important promoter of antitumor immunity
through its functions in T lymphocytes. However, the impact of T cell–expressed miR-155 on …
through its functions in T lymphocytes. However, the impact of T cell–expressed miR-155 on …
Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer
ABSTRACT MicroRNA 155 (miR-155) plays important roles in the regulation of the
development and functions of a variety of immune cells. We previously revealed a vital role …
development and functions of a variety of immune cells. We previously revealed a vital role …
microRNA-155 deficiency impairs dendritic cell function in breast cancer
J Wang, S Iwanowycz, F Yu, X Jia, S Leng… - …, 2016 - Taylor & Francis
In antitumor immunity, dendritic cells (DCs) capture, process, and present tumor antigens to
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …