The landscape of mRNA nanomedicine

X Huang, N Kong, X Zhang, Y Cao, R Langer, W Tao - Nature Medicine, 2022 - nature.com
Messenger RNA (mRNA) is an emerging class of therapeutic agent for the prevention and
treatment of a wide range of diseases. The recent success of the two highly efficacious …

Messenger RNA-based therapeutics and vaccines: what's beyond COVID-19?

D Li, C Liu, Y Li, R Tenchov, JM Sasso… - ACS Pharmacology & …, 2023 - ACS Publications
With the rapid success in the development of mRNA vaccines against COVID-19 and with a
number of mRNA-based drugs ahead in the pipelines, mRNA has catapulted to the forefront …

mRNA nanomedicine: Design and recent applications

LJ Kubiatowicz, A Mohapatra, N Krishnan… - …, 2022 - Wiley Online Library
The rational design and application of mRNA‐based medicine have recently yielded some
key successes in the clinical management of human diseases. mRNA technology allows for …

Biomedical applications of mRNA nanomedicine

Q Xiong, GY Lee, J Ding, W Li, J Shi - Nano research, 2018 - Springer
As an attractive alternative to plasmid DNA, messenger RNA (mRNA) has recently emerged
as a promising class of nucleic acid therapeutics for biomedical applications. Advances in …

Nanomedicine-based approaches for mRNA delivery

S Uchida, F Perche, C Pichon… - Molecular …, 2020 - ACS Publications
Messenger RNA (mRNA) has immense potential for developing a wide range of therapies,
including immunotherapy and protein replacement. As mRNA presents no risk of integration …

Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment

ME Karim, ST Haque, H Al-Busaidi, A Bakhtiar… - Archives of pharmacal …, 2022 - Springer
Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent
diseases ranging from cancer and Alzheimer's disease to COVID-19 with significant clinical …

Messenger RNA-based vaccines: Past, present, and future directions in the context of the COVID-19 pandemic

S Jain, A Venkataraman, ME Wechsler… - Advanced drug delivery …, 2021 - Elsevier
Abstract mRNA vaccines have received major attention in the fight against COVID-19.
Formulations from companies such as Moderna and BioNTech/Pfizer have allowed us to …

mRNA therapeutics deliver a hopeful message

Z Zhong, S Mc Cafferty, F Combes, H Huysmans… - Nano today, 2018 - Elsevier
Messenger RNA based therapeutics have the potential to cause a big revolution in medicine
as they can facilitate personalized medicines and allow patients to produce their own …

mRNA-based therapeutics: powerful and versatile tools to combat diseases

S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

mRNA-based vaccines and therapeutics for COVID-19 and future pandemics

VP Chavda, S Soni, LK Vora, S Soni, A Khadela… - Vaccines, 2022 - mdpi.com
An unheard mobilization of resources to find SARS-CoV-2 vaccines and therapies has been
sparked by the COVID-19 pandemic. Two years ago, COVID-19's launch propelled mRNA …