Shaping the Future of Antimicrobial Therapy: Harnessing the Power of Antimicrobial Peptides in Biomedical Applications

AK Tripathi, J Singh, R Trivedi, P Ranade - Journal of Functional …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) have emerged as a promising class of bioactive molecules
with the potential to combat infections associated with medical implants and biomaterials …

Application of antimicrobial peptides on biomedical implants: Three ways to pursue peptide coatings

MG Drexelius, I Neundorf - International Journal of Molecular Sciences, 2021 - mdpi.com
Biofilm formation and inflammations are number one reasons of implant failure and cause a
severe number of postoperative complications every year. To functionalize implant surfaces …

Strategies for antimicrobial peptide coatings on medical devices: A review and regulatory science perspective

M Kazemzadeh-Narbat, H Cheng… - Critical reviews in …, 2021 - Taylor & Francis
Indwelling and implanted medical devices are subject to contamination by microbial
pathogens during surgery, insertion or injection, and ongoing use, often resulting in severe …

The potential of surface-immobilized antimicrobial peptides for the enhancement of orthopaedic medical devices: a review

B Skerlavaj, G Boix-Lemonche - Antibiotics, 2023 - mdpi.com
Due to the well-known phenomenon of antibiotic resistance, there is a constant need for
antibiotics with novel mechanisms and different targets respect to those currently in use. In …

Engineered chimeric peptides as antimicrobial surface coating agents toward infection-free implants

H Yazici, MB O'Neill, T Kacar, BR Wilson… - … applied materials & …, 2016 - ACS Publications
Prevention of bacterial colonization and consequent biofilm formation remains a major
challenge in implantable medical devices. Implant-associated infections are not only a major …

Antimicrobial peptides in biomedical device manufacturing

M Riool, A de Breij, JW Drijfhout, PH Nibbering… - Frontiers in …, 2017 - frontiersin.org
Over the past decades the use of medical devices, such as catheters, artificial heart valves,
prosthetic joints, and other implants, has grown significantly. Despite continuous …

Toward infection-resistant surfaces: achieving high antimicrobial peptide potency by modulating the functionality of polymer brush and peptide

K Yu, JCY Lo, Y Mei, EF Haney, E Siren… - … applied materials & …, 2015 - ACS Publications
Bacterial infection associated with indwelling medical devices and implants is a major
clinical issue, and the prevention or treatment of such infections is challenging. Antimicrobial …

Strategies for antimicrobial peptides immobilization on surfaces to prevent biofilm growth on biomedical devices

M Nicolas, B Beito, M Oliveira, M Tudela Martins… - Antibiotics, 2021 - mdpi.com
Nosocomial and medical device-induced biofilm infections affect millions of lives and
urgently require innovative preventive approaches. These pathologies have led to the …

Antimicrobial peptides (AMP) biomaterial coatings for tissue repair

F Costa, P Gomes, MCL Martins - Peptides and proteins as biomaterials for …, 2018 - Elsevier
Modern medicine has been supported for many years by medical devices, which are
frequently the only available solution for impaired organ function or structure. Medical …

Antimicrobial peptides in the battle against orthopedic implant-related infections: A review

B Costa, G Martínez-de-Tejada, PAC Gomes… - Pharmaceutics, 2021 - mdpi.com
Prevention of orthopedic implant-related infections is a major medical challenge, particularly
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current …