Enteral versus parenteral nutrition in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

G Elke, ARH van Zanten, M Lemieux, M McCall… - Critical Care, 2016 - Springer
Background Enteral nutrition (EN) is recommended as the preferred route for early nutrition
therapy in critically ill adults over parenteral nutrition (PN). A recent large randomized …

A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial

PE Wischmeyer, M Hasselmann, C Kummerlen… - Critical care, 2017 - Springer
Background Nutrition guidelines recommendations differ on the use of parenteral nutrition
(PN), and existing clinical trial data are inconclusive. Our recent observational data show …

Combination enteral and parenteral nutrition in critically ill patients: harmful or beneficial? A systematic review of the evidence

R Dhaliwal, B Jurewitsch, D Harrietha… - Intensive care …, 2004 - Springer
Objective A combination of enteral (EN) and parenteral nutrition (PN) is often used as a
strategy to optimize nutritional intake in critically ill patients; however, the effects of this …

Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature

L Gramlich, K Kichian, J Pinilla, NJ Rodych, R Dhaliwal… - Nutrition, 2004 - Elsevier
OBJECTIVE: Nutritional support is part of the standard of care for the critically ill adult
patient. In the average patient in the intensive care unit who has no contraindications to …

Supplemental parenteral nutrition versus usual care in critically ill adults: a pilot randomized controlled study

EJ Ridley, AR Davies, R Parke, M Bailey, C McArthur… - Critical care, 2018 - Springer
Background In the critically ill, energy delivery from enteral nutrition (EN) is often less than
the estimated energy requirement. Parenteral nutrition (PN) as a supplement to EN may …

Close to recommended caloric and protein intake by enteral nutrition is associated with better clinical outcome of critically ill septic patients: secondary analysis of a …

G Elke, M Wang, N Weiler, AG Day, DK Heyland - Critical Care, 2014 - Springer
Introduction Current international sepsis guidelines recommend low-dose enteral nutrition
(EN) for the first week. This contradicts other nutrition guidelines for heterogenous groups of …

Parenteral vs. enteral nutrition in the critically ill patient: a meta-analysis of trials using the intention to treat principle

F Simpson, GS Doig - Intensive care medicine, 2005 - Springer
Objective Controversy surrounds the use of parenteral nutrition in critical illness. Previous
overviews used composite scales to identify high-quality trials, which may mask important …

Medical nutrition therapy and clinical outcomes in critically ill adults: a European multinational, prospective observational cohort study (EuroPN)

M Matejovic, O Huet, K Dams, G Elke… - Critical Care, 2022 - Springer
Background Medical nutrition therapy may be associated with clinical outcomes in critically
ill patients with prolonged intensive care unit (ICU) stay. We wanted to assess nutrition …

Combination of enteral and parenteral nutrition in the acute phase of critical illness: an updated systematic review and meta‐analysis

A Hill, DK Heyland, LA Ortiz Reyes… - Journal of Parenteral …, 2022 - Wiley Online Library
Background Uncertainty remains about the best route and timing of medical nutrition therapy
in the acute phase of critical illness. Early combined enteral nutrition (EN) and parenteral …

Association between early nutrition support and 28-day mortality in critically ill patients: the FRANS prospective nutrition cohort study

E Pardo, T Lescot, JC Preiser, P Massanet, A Pons… - Critical Care, 2023 - Springer
Background Current guidelines suggest the introduction of early nutrition support within the
first 48 h of admission to the intensive care unit (ICU) for patients who cannot eat. In that …