Variants in the glucocerebrosidase (GBA) gene are the most common genetic risk factor for
Parkinson disease (PD). These include pathogenic variants causing Gaucher disease …

Objective Mutations in the glucocerebrosidase (GBA) gene are divided into mild and severe
(mGBA, sGBA) based on their contribution to the phenotype of Gaucher disease (GD) …

The presence of mutations in glucocerebrosidase (GBA) gene is a known factor increasing
the risk of developing Parkinson's disease (PD). Mutations carriers have earlier disease …

Background and purpose Variants in the glucocerebrosidase (GBA) gene are recognized as
a common and important genetic risk factor for Parkinson disease (PD). However, the impact …

Heterozygous variants in the glucocerebrosidase GBA1 gene are an increasingly
recognized risk factor for Parkinson's disease (PD). Due to the GBAP1 pseudogene, which …

It is reported that both the homozygous and heterozygous states of GBA mutations which are
the causes of Gaucher disease (GD) are linked to the risk of PD. However, the GBA variant …

Objective Variants in the glucocerebrosidase (GBA) gene are the most common and
significant risk factor for Parkinson's disease (PD). However, the impact of GBA variants on …

The discovery of glucocerebrosidase (GBA1) mutations as the greatest numerical genetic
risk factor for the development of Parkinson disease (PD) resulted in a paradigm shift within …

GBA variants are associated with increased risk and earlier onset of Parkinson's disease
(PD), and more rapid disease progression especially with “severe” variants typified by p …

Objective To test the relationship between clinically relevant types of GBA mutations (none,
risk variants, mild mutations, severe mutations) and β-glucocerebrosidase activity in patients …