A high-quality Ixodes scapularis genome advances tick science

S De, SB Kingan, C Kitsou, DM Portik, SD Foor… - Nature Genetics, 2023 - nature.com
Ixodes spp. and related ticks transmit prevalent infections, although knowledge of their
biology and development of anti-tick measures have been hindered by the lack of a high …

The Ixodes scapularis Genome Project: an opportunity for advancing tick research

CA Hill, SK Wikel - Trends in parasitology, 2005 - cell.com
The Ixodes scapularis Genome Project (IGP), the first to sequence a tick genome, will
provide an unparalleled resource for studying tick biology and tick–host–pathogen …

A transcriptome-based phylogenetic study of hard ticks (Ixodidae)

NP Charrier, A Hermouet, C Hervet, A Agoulon… - Scientific reports, 2019 - nature.com
Hard ticks are widely distributed across temperate regions, show strong variation in host
associations, and are potential vectors of a diversity of medically important zoonoses, such …

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

M Gulia-Nuss, AB Nuss, JM Meyer… - Nature …, 2016 - nature.com
Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

Tick genomics: the Ixodes genome project and beyond

JP Van Zee, NS Geraci, FD Guerrero, SK Wikel… - International journal for …, 2007 - Elsevier
Ticks and mites (subphylum Chelicerata; subclass Acari) include important pests of animals
and plants worldwide. The Ixodes scapularis (black-legged tick) genome sequencing project …

Large-scale comparative analyses of tick genomes elucidate their genetic diversity and vector capacities

N Jia, J Wang, W Shi, L Du, Y Sun, W Zhan, JF Jiang… - Cell, 2020 - cell.com
Among arthropod vectors, ticks transmit the most diverse human and animal pathogens,
leading to an increasing number of new challenges worldwide. Here we sequenced and …

Evolutionary insights into the tick hologenome

S Díaz-Sánchez, A Estrada-Peña, A Cabezas-Cruz… - Trends in …, 2019 - cell.com
Recently, our knowledge of the composition and complexity of tick microbial communities
has increased and supports microbial impact on tick biology. Results support a phylogenetic …

Grappling with the tick microbiome

S Narasimhan, A Swei, S Abouneameh, U Pal… - Trends in …, 2021 - cell.com
Ixodes scapularis and Ixodes pacificus are the predominant vectors of multiple human
pathogens, including Borrelia burgdorferi, one of the causative agents of Lyme disease in …

Immunity-related genes in Ixodes scapularis—perspectives from genome information

AA Smith, U Pal - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
Ixodes scapularis, commonly known as the deer tick, transmits a wide array of human and
animal pathogens including Borrelia burgdorferi. Despite substantial advances in our …

Lack of genetic structure among Eurasian populations of the tick Ixodes ricinus contrasts with marked divergence from north-African populations

R Noureddine, A Chauvin, O Plantard - International journal for …, 2011 - Elsevier
Host–parasite interactions may select for significant novel mutations with major evolutionary
consequences for both partners. In poor active dispersers such as ticks, their population …