Despite enormous efforts employing various approaches, the molecular pathology in the
schizophrenia brain remains elusive. On the other hand, the knowledge of the association …

Over the last decade, transcriptome studies of postmortem tissue from subjects with
schizophrenia revealed that synaptic, mitochondrial, immune system, gamma-aminobutyric …

Postmortem CNS studies have begun to unravel changes in the epigenetic regulation of
gene expression that may be central to how gene–environment interactions contribute to the …

Schizophrenia is an illness where the clinical signs and symptoms, course, and cognitive
characteristics are well described. Successful pharmacological treatments do exist, even …

New findings in schizophrenia genetics are based on genome-wide association studies
(GWAS), research into DNA copy number variations (CNVs), and endophenotypes. More …

Schizophrenia is a common mental illness resulting from a complex interplay of genetic and
environmental risk factors. Establishing its primary molecular and cellular aetiopathologies …

Post-mortem brain investigations of schizophrenia have generated swathes of data in the
last few decades implicating candidate genes and protein. However, the relation of these …

Context Schizophrenia is a common, highly heritable, neurodevelopmental mental illness,
characterized by genetic heterogeneity. Objective To identify abnormalities in the …

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

Schizophrenia genome-wide association studies (GWAS) have identified common SNPs,
rare copy number variants (CNVs) and a large polygenic contribution to illness risk, but …