The pathogenesis of human leukocyte antigen (HLA)-B27-associated diseases such as
acute anterior uveitis (AAU) and ankylosing spondylitis (AS) remains poorly understood …

Acute anterior uveitis (AAU) and the spondyloarthritis (SpA) subtypes ankylosing spondylitis,
reactive arthritis and psoriatic arthritis are among the inflammatory diseases affected by the …

The microbiome is strongly implicated in a broad spectrum of immune-mediated diseases.
Data support the concept that HLA molecules shape the microbiome. We provide …

There has been steady progress in understanding the pathogenesis, clinical features, and
effective treatment of acute anterior uveitis (AU) over the past 5 years. Large gene wide …

Spondyloarthritis (SpA) is a group of immune mediated inflammatory diseases with a strong
association to the major histocompatibility (MHC) class I molecule, HLA-B27. Although the …

The human gut harbors a tremendously diverse microbial community that correlates with
and even modulates many health-related processes. Disruption of this ecological …

HLA-B27 is the allele most frequently associated with human anterior uveitis. The majority of
HLA-B27-positive [acute anterior uveitis (AAU)] patients develop clinically distinct symptoms …

Abstract Purpose of Review Ankylosing spondyloarthritis (AS) is a chronic inflammatory
disease that involves the axial joints and entheses. Extra-spinal manifestations such as …

Acute anterior uveitis (AAU) is the commonest type of uveitis and HLA-B27 AAU is the most
frequently recognized type of acute anterior uveitis and anterior uveitis overall. Recent …

Acute anterior uveitis is the most common form of uveitis. HLA-B27-associated acute anterior
uveitis is a distinct clinical entity that has wide-ranging medical significance due to its ocular …