Understanding the detailed mechanism behind every human disease, disorder, defect, and
deficiency is a daunting task concerning the clinical diagnostic tools for patients. Hence, a …

Advances in genomics and next-generation sequencing have provided clinical researchers
with unprecedented opportunities to understand the molecular basis of human genetic …

Zebrafish have been widely used as a model system for studying developmental processes,
but in the last decade, they have also emerged as a valuable system for modeling human …

This is a good thing because animals show other organisms how to stay healthy in their
environment. Biologists can learn more about a lot ofdifferent biological processes by …

Rare genetic diseases are a group of pathologies with often unmet clinical needs. Even if
rare by a single genetic disease (from 1/2000 to 1/more than 1,000,000), the total number of …

[Frontiers in Bioscience 7, d827-833, April 1, 2002] 827 THE ZEBRAFISH AS A MODEL
SYSTEM FOR HUMAN DISEASE Alister C. Ward1,2 a Page 1 [Frontiers in Bioscience 7 …

Implications Because of its fully sequenced genome, easy genetic manipulation, high
fecundity, external fertilization and rapid development, and nearly transparent embryo …

Five years after the launch of the Disease Models & Mechanisms (DMM) Special Issue on
zebrafish as a disease model, the field has progressed significantly. Zebrafish have been …

Personalized medicine is currently one of the most promising tools which give hope to
patients with no suitable or no available treatment. Patient-specific approaches are …

Much of medical research relies on animal models to deepen knowledge of the causes of
animal and human diseases, as well as to enable the development of innovative therapies …