Potential of multi-strain probiotics extract as an anti-inflammatory agent through inhibition of macrophage migration inhibitory factor activity

D Nyotohadi, T Kok - Functional Foods in Health and Disease, 2023 - ffhdj.com
Background: Probiotics are reported to have a role for improving health conditions and
reduce the risk of diseases associated with inflammation. However, how they affect …

Identification and structure–activity relationships of dietary flavonoids as human macrophage migration inhibitory factor (MIF) inhibitors

L Yang, D Guo, C Fan - Journal of Agricultural and Food …, 2021 - ACS Publications
Dietary flavonoids are known to have anti-inflammatory and anticancer effects, but their
influences on human macrophage migration inhibitory factor (MIF), a vital proinflammatory …

Ellagic acid, a dietary polyphenol, inhibits tautomerase activity of human macrophage migration inhibitory factor and its pro-inflammatory responses in human …

S Sarkar, AA Siddiqui, S Mazumder, R De… - Journal of agricultural …, 2015 - ACS Publications
Ellagic acid (EA), a phenolic lactone, inhibited tautomerase activity of human macrophage
migration inhibitory factor (MIF) noncompetitively (K i= 1.97±0.7 μM). The binding of EA to …

Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action

H Ouertatani-Sakouhi, F El-Turk, B Fauvet… - Journal of Biological …, 2010 - ASBMB
Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine, is considered an
attractive therapeutic target in multiple inflammatory and autoimmune disorders. In addition …

[HTML][HTML] Human single-chain variable fragment antibody inhibits macrophage migration inhibitory factor tautomerase activity

M Tarasuk, O Poungpair… - International …, 2014 - spandidos-publications.com
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine, secreted from a
variety of immune cells, that regulates innate and adaptive immune responses. Elevation of …

Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of …

A Alam, S Haldar, HV Thulasiram, R Kumar… - Journal of Biological …, 2012 - ASBMB
Macrophage migration inhibitory factor (MIF) is responsible for proinflammatory reactions in
various infectious and non-infectious diseases. We have investigated the mechanism of anti …

Repurposing old drugs as novel inhibitors of human MIF from structural and functional analysis

L Yang, C Yang, L Wang, Z Yang, D Guo… - Bioorganic & Medicinal …, 2022 - Elsevier
Human macrophage migration inhibitory factor (MIF) is an important pro-inflammatory
cytokine that plays multiple pleiotropic functions. It is considered as a promising therapeutic …

Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats

XR Huang, CWC Hui, YX Chen, B Chun, Y Wong… - Gastroenterology, 2001 - Elsevier
Background & Aims: Macrophage migration inhibitory factor (MIF) has been shown to play a
pivotal role in inflammatory and immune-mediated diseases. This study investigates the role …

Novel pathophysiological aspects of macrophage migration inhibitory factor

J Nishihira - International Journal of Molecular …, 1998 - spandidos-publications.com
Macrophage migration inhibitory factor (MIF) was the first T-cell-derived soluble lymphokine
to be identified. It was originally found to inhibit the migration of macrophages and activate …

Aza-derivatives of resveratrol are potent macrophage migration inhibitory factor inhibitors

Y Fujita, R Islam, K Sakai, H Kaneda, K Kudo… - Investigational new …, 2012 - Springer
Summary Resveratrol (3, 4′, 5-trihydroxy-trans-stilbene), a natural phytoalexin found in
grapes and wine, has anti-proliferative activity on human-derived cancer cells. In our study …