Since the early stages of the pandemic, hydroxychloroquine (HCQ), a widely used drug with
good safety profile in clinic, has come to the forefront of research on drug repurposing for …

Hydroxychloroquine (HCQ), a derivative of chloroquine (CQ), is an antimalarial and
antirheumatic drug. Since there is limited data available on the genotoxicity of HCQ, in the …

Abstract Hydroxychloroquine (HCQ) and Chloroquine (CQ) are two anti-malarial drugs that
are now being extensively used by front-line healthcare workers and other common people …

Chloroquine (CHQ) is a commonly used antimalarial agent. We evaluated the genotoxic
potential of CHQ using chromosome aberration (CA), micronucleus (MN), and sperm head …

The genotoxic effect of chloroquine (CQ), a 4-aminoquinoline antimalarial drug was
investigated in rat liver cells using the alkaline comet assay. Chloroquine (0–1000 μmol/L) …

Molnupiravir is an antiviral agent recently used for treating coronavirus disease 2019
(COVID-19). Here, we demonstrate that N 4-hydroxycytidine (NHC), a molnupiravir …

Background Cancer is a global health problem accounting for nearly one in six deaths
worldwide. Conventional treatments together with new therapies have increased survival to …

The human genome is constantly attacked by endogenous and exogenous agents
(ultraviolet light, xenobiotics, reactive oxygen species), which can induce chemical …

COVID-19 is a pandemic with no end in sight. There is only one approved antiviral agent but
global stocks are deemed insufficient. Despite in vitro antiviral activity, clinical trials of …

Background Hydroxychloroquine (HCQ) is a cornerstone therapy for systemic lupus
erythematosus (SLE) and rheumatoid arthritis (RA). This study aimed to investigate the …