Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno …

S Hendry, R Salgado, T Gevaert… - Advances in anatomic …, 2017 - journals.lww.com
Assessment of the immune response to tumors is growing in importance as the prognostic
implications of this response are increasingly recognized, and as immunotherapies are …

Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the international …

S Hendry, R Salgado, T Gevaert… - Advances in anatomic …, 2017 - journals.lww.com
Assessment of tumor-infiltrating lymphocytes (TILs) in histopathologic specimens can
provide important prognostic information in diverse solid tumor types, and may also be of …

Role of tumor-infiltrating lymphocytes in patients with solid tumors: Can a drop dig a stone?

G Badalamenti, D Fanale, L Incorvaia, N Barraco… - Cellular …, 2019 - Elsevier
In recent years, multiple strategies for eliciting anti-tumor immunity have been developed in
different clinical studies. Currently, immunotherapy was clinically validated as effective …

[HTML][HTML] Tumor-infiltrating lymphocytes in head and neck cancer: ready for prime time?

A Almangush, S De Keukeleire, S Rottey, L Ferdinande… - Cancers, 2022 - mdpi.com
Simple Summary The immune response has been shown to be a promising indicator to
predict the clinical behavior of many cancers, including head and neck cancer. Tumor …

[HTML][HTML] The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014

R Salgado, C Denkert, S Demaria, N Sirtaine… - Annals of oncology, 2015 - Elsevier
Evidence is strengthening for the morphological evaluation of tumor infiltrating lymphocytes
(TILs) in breast cancer. Herein, the concepts for TILs assessment are laid out by pathologists …

[HTML][HTML] Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and …

MV Dieci, N Radosevic-Robin, S Fineberg… - Seminars in cancer …, 2018 - Elsevier
Morphological evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer is gaining
momentum as evidence strengthens the clinical relevance of this immunological biomarker …

[HTML][HTML] Clinical validity and utility of tumor-infiltrating lymphocytes in routine clinical practice for breast cancer patients: current and future directions

L Wein, P Savas, SJ Luen, B Virassamy… - Frontiers in …, 2017 - frontiersin.org
The interest in tumor-infiltrating lymphocytes (TILs) as a prognostic biomarker in breast
cancer has grown in recent years. Biomarkers must undergo comprehensive evaluation in …

Variation of tumor-infiltrating lymphocytes in human cancers: controversy on clinical significance

T Sasada, S Suekane - Immunotherapy, 2011 - Future Medicine
Tumors develop and progress under the influence of a microenvironment comprising a
variety of immune cell subsets and their products. Recent studies have shown that tumor …

Trial watch: Prognostic and predictive value of the immune infiltrate in cancer

L Senovilla, E Vacchelli, J Galon, S Adjemian… - …, 2012 - Taylor & Francis
Solid tumors are constituted of a variety of cellular components, including bona fide
malignant cells as well as endothelial, structural and immune cells. On one hand, the tumor …

[HTML][HTML] Tumor infiltrating lymphocytes across breast cancer subtypes: current issues for biomarker assessment

C Valenza, B Taurelli Salimbeni, C Santoro, D Trapani… - Cancers, 2023 - mdpi.com
Simple Summary Tumor-infiltrating lymphocytes (TILs) are immune cells that can be
involved in the anti-tumor response and are presently viewed as a promising, inexpensive …