Killer cell immunoglobulin-like receptors (KIRs) are expressed predominantly on natural
killer cells, where they play a key role in the regulation of innate immune responses. Recent …

Virus-specific CD8+ T cells play a central role in the control of viral infections, including
human immunodeficiency virus type 1 (HIV-1) infection. However, despite the presence of …

Killer cell immunoglobulin-like receptors (KIRs) influence both innate and adaptive
immunity. But while the role of KIRs in NK-mediated innate immunity is well-documented, the …

BACKGROUND There is increasing evidence, in transgenic mice and in vitro, that inhibitory
killer cell immunoglobulin-like receptors (iKIRs) can modulate T cell responses …

Several studies support a role for specific killer immunoglobulin-like receptor (KIR)–HLA
combinations in protection from HIV infection and slower progression to AIDS. Natural killer …

ABSTRACT A flurry of recent reports on the role of activating and inhibitory forms of the killer
cell immunoglobulin-like receptors (KIR) in natural killer (NK) cell activity against human …

Natural killer (NK) cells control viral infection in part through the interaction between killer
cell immunoglobulin-like receptors (KIRs) and their human leukocyte antigen (HLA) ligands …

Killer-cell inhibitory receptors (KIRs) are a new family of major histocompatibility complex
(MHC) class I-specific receptors. KIRs allow natural killer cells to identify and lyse self cells …

The killer cell immunoglobulin-like receptors (KIR) are a recently discovered family of
activating and inhibitory receptors that control natural killer (NK) cell function. KIR exist as a …

ABSTRACT NK cells are critical in the early containment of viral infections. Epidemiological
and functional studies have shown an important role of NK cells expressing specific killer …