U Abadi, O Yarchovsky-Dolberg… - Clinical and Applied …, 2015 - journals.sagepub.com
Immune thrombocytopenia (ITP) is a rare autoimmune disorder with an incidence of 3 to 5 per 100 000 individuals. In children, the disease is self-limited and is most commonly virus …
E Lo, S Deane - Autoimmunity reviews, 2014 - Elsevier
Immune thrombocytopenia, or ITP, has been recognized as a clinical entity for centuries, and the importance of humoral mechanisms in the pathophysiology of ITP has been recognized …
S Audia, M Mahévas, M Nivet, S Ouandji… - …, 2021 - journals.lww.com
Immune thrombocytopenia (ITP) is a rare autoimmune disease due to both a peripheral destruction of platelets and an inappropriate bone marrow production. Although the primary …
A Zufferey, R Kapur, JW Semple - Journal of clinical medicine, 2017 - mdpi.com
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated …
A Salama - Expert review of hematology, 2011 - Taylor & Francis
Traditional treatment of primary (idiopathic) immune thrombocytopenia (ITP) predominantly consists of immune suppression and/or modulation. In addition, many treated patients …
D Martínez-Carballeira, Á Bernardo, A Caro, I Soto… - Hematology …, 2024 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by an isolated decrease in the platelet count and an increased risk of bleeding. The pathogenesis is …
H Al‐Samkari - American Journal of Hematology, 2024 - Wiley Online Library
Although the development and regulatory approval of the thrombopoietin receptor agonists revolutionized aspects of the immune thrombocytopenia (ITP) treatment landscape over the …
M Perera, T Garrido - Hematology, 2017 - Taylor & Francis
Objectives: Classically, immune thrombocytopenia (ITP) was thought to be caused by the destruction and insufficient production of platelets, as mediated by autoantibodies. More …
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by antibody- mediated platelet destruction. The platelet, as an accessible target, has made ITP an …