Historically marginalized racial and ethnic groups and Indigenous peoples are burdened by
significant health inequities that are compounded by their underrepresentation in genetic …

Cardiovascular diseases remain the leading cause of mortality and a major contributor to
preventable deaths worldwide. The dominant modifiable risk factors and the social and …

Genomics research has improved our understanding of the genetic basis for human traits
and diseases. This progress is now being translated into clinical care as we move toward a …

Objective: The design, overall methods, and major phenotypes for the all-African-American
Jackson Heart Study (JHS) are detailed. Methods: Participants were enrolled from the three …

Background Heart Healthy Lenoir is a transdisciplinary project aimed at creating long-term,
sustainable approaches to reduce cardiovascular disease risk disparities in Lenoir County …

After nearly a decade of genome-wide association studies, no assessment has yet been
made of their contribution toward an explanation of the most prominent racial health …

Genome-wide association studies have revolutionized our understanding of the genetic
underpinnings of cardiometabolic disease. Yet, the inadequate representation of individuals …

The medical literature is replete with remarkable, even sensationally defined, differences in
disease burden and health outcomes as a function of race and ethnicity. Many of those …

Background All of Us is a novel research program that aims to accelerate research in
populations traditionally underrepresented in biomedical research. Our objective was to …

Disparities persist in cardiovascular disease, and it is difficult to separate socioeconomic
status from race/ethnicity or genetic factors. Blacks have more hypertension, with higher …