In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Pharmacological response depends on multiple factors and one of them is sex–gender.
Data on the specific effects of sex–gender on pharmacokinetics, as well as the safety and …

Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

This is the very first book to deal with sex and gender differences in drug therapy-an
increasingly recognized medical need. It starts with an overview on S/G in clinical …

In recent years, it has become clear that women and men may differ for drug response. Also,
there is an increasing recognition on the role of sex hormones on pharmacokinetics and …

Clinically relevant adverse drug reactions differ between men and women. The underlying
physiological and pharmacological processes contributing to these differences are …

Earlier research has presumed that the male and female biology is similar in most organs
except the reproductive system, leading to major misconceptions in research interpretations …

Clinical data suggest that gender dimorphic profiles are emerging in terms of both drug
efficacy and adverse drug reactions (ADRs). With an increasing emphasis on individualised …

Gender-related differences in pharmacokinetics have frequently been considered as
potentially important determinants for the clinical effectiveness of drug therapy. The …

Significant differences that exist between the sexes affect the prevalence, incidence and
severity of a broad range of diseases and conditions. Men and women also differ in their …