Background The association between chronic kidney disease (CKD) and functional status
may change as a function of the equation used to estimate glomerular filtration rate (eGFR) …

Objective Determine the relationship of renal function with frailty using different formulas for
estimated glomerular filtration rate (eGFR). Methods Individuals who were 60-years-old or …

The equations for estimating kidney function have become very popular in the last decade.
However, the clinical and prognostic meaning of these measures may be very different in …

Background Use of serum creatinine to estimate GFR may lead to underestimation of the
association between self-reported frailty and kidney function. Our objectives were to …

Background The burden of chronic kidney disease is highest among older adults but the
significance of a diminished level of kidney function in this heterogeneous population is …

Frailty is defined as a medical syndrome of multisystem dysregulation and is manifested as
compromised resistance to stressors that increases vulnerability to dependence and …

Background: Estimated glomerular filtration rate (eGFR) calculated using creatinine and
cystatin C often differ in older adults. We hypothesized that older adults with cystatin-based …

Background. As creatinine-based estimates of renal function are inaccurate in older adults,
an alternative is an estimated glomerular filtration rate (eGFRcys) based on cystatin C. We …

Background: Chronic kidney disease (CKD) is increasingly common and disproportionately
affects older adults. The contribution of kidney disease to the functional impairment noted in …

Rationale & Objective The difference in the estimated glomerular filtration rate based on
cystatin C and that based on creatinine (eGFRDiff) is known to be associated with frailty and …