The thalamic reticular nucleus (TRN), the major source of thalamic inhibition, regulates
thalamocortical interactions that are critical for sensory processing, attention and cognition 1 …

The activity of the GABAergic neurons of the thalamic reticular nucleus (TRN) has long been
known to play important roles in modulating the flow of information through the thalamus and …

In spite of the uniform appearance of sleep as a behavior, the sleeping brain does not
produce electrical activities in unison. Different types of brain rhythms arise during sleep and …

Most sensory information destined for the neocortex is relayed through the thalamus, where
considerable transformation occurs,. One means of transformation involves interactions …

During non-rapid eye movement (NREM) sleep, synchronous synaptic activity in the
thalamocortical network generates predominantly low-frequency oscillations (< 4 Hz) that …

Diagnoses of behavioral disorders such as autism spectrum disorder and schizophrenia are
based on symptomatic descriptions that have been difficult to connect to mechanism …

Behavioral state is known to influence interactions between thalamus and cortex, which are
important for sensation, action, and cognition. The thalamic reticular nucleus (TRN) is …

The thalamus is the central communication hub of the forebrain and provides the cerebral
cortex with inputs from sensory organs, subcortical systems and the cortex itself. Multiple …

Corticothalamic pathways, responsible for the top-down control of the thalamus, have a
canonical organization such that every cortical region sends output from both layer 6 (L6) …

The thalamic reticular nucleus (TRN) is hypothesized to regulate neocortical rhythms and
behavioral states. Using optogenetics and multi-electrode recording in behaving mice, we …