Experience and challenges from clinical trials with malaria vaccines in Africa

G Mwangoka, B Ogutu, B Msambichaka, T Mzee… - Malaria journal, 2013 - Springer
Malaria vaccines are considered amongst the most important modalities for potential
elimination of malaria disease and transmission. Research and development in this field has …

Clinical development of malaria vaccines: should earlier trials be done in malaria endemic countries?

R Chilengi - Human Vaccines, 2009 - Taylor & Francis
Clinical development of malaria vaccines has had remarkable achievements in the past
decade, but an efficacious vaccine is yet to be licensed. There are many scientific and …

Malaria vaccines in Africa

WL Kilama - Acta tropica, 2003 - Elsevier
Besides being a leading cause of morbidity and mortality, malaria is also a cause and
consequence of rampant poverty in Africa, where current control efforts are mainly frustrated …

[HTML][HTML] Methods for determining vaccine efficacy and effectiveness and the main barriers to developing a fully deployable malaria vaccine

C Guinovart, PL Alonso - … and Defeating the Intolerable Burden of …, 2007 - ncbi.nlm.nih.gov
The past few years have witnessed the appearance of public-private partnerships and a
significant increase of resources devoted to the development of malaria vaccines. Lessons …

Malaria vaccines in development

WR Ballou - Expert opinion on emerging drugs, 2005 - Taylor & Francis
The recent infusion of public and private funding for malaria vaccine development has
greatly accelerated the pace at which candidate malaria vaccines are entering the clinic …

[HTML][HTML] Towards an African-driven malaria vaccine development program: history and activities of the African Malaria Network Trust (AMANET)

WL Kilama, R Chilengi, CL Wanga - … to Volume 77 (6) of American …, 2007 - ncbi.nlm.nih.gov
The African Malaria Network Trust (AMANET), whose mission is to promote capacity
strengthening of African malaria research institutions, was founded in 2002 and is currently …

A malaria vaccine for Africa—an important step in a century-long quest

PL Alonso, KL O'Brien - New England Journal of Medicine, 2022 - Mass Medical Soc
A Malaria Vaccine for Africa — An Important Step in a Century-Long Quest | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Malaria vaccine: A step toward elimination

H Jindal, B Bhatt, JS Malik, S Sk… - Human Vaccines & …, 2014 - Taylor & Francis
Malaria has long been recognized as a public health problem. At the community level, vector
control, and antimalarial medicines are the main means for reducing incidence, morbidity …

Clinical malaria vaccine development

RW Sauerwein - Immunology letters, 2009 - Elsevier
Malaria is a major economic and public health problem in mainly sub-Saharan Africa.
Globally 300–500 million new infections occur each year with 1–3 million fatal cases in …

A review of human vaccine research and development: malaria

MP Girard, ZH Reed, M Friede, MP Kieny - Vaccine, 2007 - Elsevier
The last several years have seen significant progress in the development of vaccines
against malaria. Most recently, proof-of-concept of vaccine-induced protection from malaria …