Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention

Z Khatoon, CD McTiernan, EJ Suuronen, TF Mah… - Heliyon, 2018 - cell.com
In living organisms, biofilms are defined as complex communities of bacteria residing within
an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the …

A review of bacterial biofilms and their role in device-associated infection

K Vickery, H Hu, AS Jacombs, DA Bradshaw… - Healthcare infection, 2013 - Elsevier
Background Most of the world's bacteria live in biofilms, three-dimensional clusters attached
to surfaces. Manyhospital-acquired infections are associated with biofilm infections of …

Prevention and control of biofilm-based medical-device-related infections

I Francolini, G Donelli - FEMS Immunology & Medical …, 2010 - academic.oup.com
Biofilms play a pivotal role in healthcare-associated infections, especially those related to
the implant of medical devices, such as intravascular catheters, urinary catheters and …

Novel approaches to combat medical device-associated biofilms

X Li, L Sun, P Zhang, Y Wang - Coatings, 2021 - mdpi.com
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …

Understanding biofilms and novel approaches to the diagnosis, prevention, and treatment of medical device-associated infections

YM Wi, R Patel - Infectious Disease Clinics, 2018 - id.theclinics.com
Medical device-associated infections are one of the most common and feared complications
in medical practice. The treatment of medical device-related infections is notoriously …

Recent advances in the control of clinically important biofilms

K Krukiewicz, A Kazek-Kęsik… - International journal of …, 2022 - mdpi.com
Biofilms are complex structures formed by bacteria, fungi, or even viruses on biotic and
abiotic surfaces, and they can be found in almost any part of the human body. The …

Novel strategies for the prevention and treatment of biofilm related infections

M Chen, Q Yu, H Sun - International journal of molecular sciences, 2013 - mdpi.com
Biofilm formation by human bacterial pathogens on implanted medical devices causes major
morbidity and mortality among patients, and leads to billions of dollars in healthcare cost …

Nanomaterials for treating bacterial biofilms on implantable medical devices

HM Tran, H Tran, MA Booth, KE Fox, TH Nguyen… - Nanomaterials, 2020 - mdpi.com
Bacterial biofilms are involved in most device-associated infections and remain a challenge
for modern medicine. One major approach to addressing this problem is to prevent the …

Functionalized biomaterials to combat biofilms

D Huang, J Wang, K Ren, J Ji - Biomaterials Science, 2020 - pubs.rsc.org
Pathogenic microbial biofilms that readily form on implantable medical devices or human
tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive …

Bacterial and fungal biofilm infections

AS Lynch, GT Robertson - Annu. Rev. Med., 2008 - annualreviews.org
Biofilms are communal structures of microorganisms encased in an exopolymeric coat that
form on both natural and abiotic surfaces and have been associated with a variety of …