A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain

J Liu, F Li, Y Wang, L Pan, P Lin, B Zhang… - Nature …, 2020 - nature.com
Extracellular potassium concentration affects the membrane potential of neurons, and, thus,
neuronal activity. Indeed, alterations of potassium levels can be related to neurological …

A highly sensitive and selective nanosensor for near-infrared potassium imaging

J Liu, L Pan, C Shang, B Lu, R Wu, Y Feng, W Chen… - Science …, 2020 - science.org
Potassium ion (K+) concentration fluctuates in various biological processes. A number of K+
probes have been developed to monitor such fluctuations through optical imaging. However …

K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator

P Padmawar, X Yao, O Bloch, GT Manley… - Nature Methods, 2005 - nature.com
We synthesized a water-soluble, long-wavelength K+ sensor, TAC-Red, consisting of
triazacryptand coupled to 3, 6-bis (dimethylamino) xanthylium, whose fluorescence …

Visualizing sodium dynamics in isolated cardiomyocytes using fluorescent nanosensors

JM Dubach, S Das, A Rosenzweig… - Proceedings of the …, 2009 - National Acad Sciences
Regulation of sodium flux across the cell membrane plays a vital role in the generation of
action potentials and regulation of membrane excitability in cells such as cardiomyocytes …

A SERS Optophysiological Probe for the Real‐Time Mapping and Simultaneous Determination of the Carbonate Concentration and pH Value in a Live Mouse Brain

W Wang, F Zhao, M Li, C Zhang, Y Shao… - Angewandte …, 2019 - Wiley Online Library
To have a profound understanding of the physiological and pathological processes in a
brain, both chemical and electrical signals need to be recorded, but this is still very …

[HTML][HTML] Nanowire-Based Electrode for Acute In Vivo Neural Recordings in the Brain

DB Suyatin, L Wallman, J Thelin, CN Prinz, H Jörntell… - PLoS …, 2013 - journals.plos.org
We present an electrode, based on structurally controlled nanowires, as a first step towards
developing a useful nanostructured device for neurophysiological measurements in vivo …

Nanotechnology and neurophysiology

MR Angle, B Cui, NA Melosh - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Nanofabrication is capable of patterning devices at the same length-scales as
cellular components (ie 10 s of nanometers).•Nanoscale devices can be used to measure …

An electrochemophysiological microarray for real‐time monitoring and quantification of multiple ions in the brain of a freely moving rat

F Zhao, Y Liu, H Dong, S Feng, G Shi, L Lin… - Angewandte …, 2020 - Wiley Online Library
Herein, we present an electrochemophysiological microarray (ECPM) for real‐time mapping
and simultaneous quantification of chemical signals for multiple ions in the deep brain of a …

Evaluating the potential of using quantum dots for monitoring electrical signals in neurons

AL Efros, JB Delehanty, AL Huston, IL Medintz… - Nature …, 2018 - nature.com
Success in the projects aimed at providing an advanced understanding of the brain is
directly predicated on making critical advances in nanotechnology. This Perspective …

Nanoelectronics-biology frontier: From nanoscopic probes for action potential recording in live cells to three-dimensional cyborg tissues

X Duan, TM Fu, J Liu, CM Lieber - Nano today, 2013 - Elsevier
Semiconductor nanowires configured as the active channels of field-effect transistors (FETs)
have been used as detectors for high-resolution electrical recording from single live cells …