The biguanide metformin is the most commonly used antidiabetic drug. Recent studies show
that metformin not only improves chronic inflammation by improving metabolic parameters …

Background: Metformin, a widely prescribed blood glucose normalizing antidiabetic drug, is
now beginning to receive increasing attention due to its anti-inflammatory properties …

Metformin is a biguanide drug widely used as the initial treatment of type 2 diabetes. Despite
its widespread use, its precise mechanisms of action remain incompletely characterised. Its …

Metformin is an oral hypoglycemic agent which is most widely used as first-line therapy for
type 2 diabetes. Metformin improves hyperglycemia by suppressing hepatic glucose …

It has become widely accepted that inflammation is a driving force behind a variety of
chronic diseases, such as cardiovascular disease, diabetes, kidney disease, cancer …

Type 2 diabetes mellitus (T2DM) is the most common chronic metabolic condition. Several
genetic and environmental factors are involved in developing T2DM. Aging, inflammation …

Metformin is a biguanide family member used in the treatment of type 2 diabetes and one of
the most widely prescribed antidiabetes drugs. This drug increases the peripheral uptake of …

The most well‐known mechanism of metformin action, one of the most commonly prescribed
antidiabetic drugs, is adenosine monophosphate‐activated protein kinase activation; …

Background Metformin has good anti-hyperglycemic effectiveness, but does not induce
hypoglycemia, is very safe, and has become the preferred drug for the treatment of type 2 …

Metformin (dimethyl biguanide) is a synthetic derivative of guanidine, isolated from the
extracts of Galega officinalis, a plant with a prominent antidiabetic effect. Since its discovery …