Periprosthetic joint infection (PJI) is a significant challenge in orthopaedic surgery. Several
operations, protracted treatment, and the high associated morbidity have a very detrimental …

Peri‐prosthetic joint infection (PJI) is one of the most serious and dreaded complications
after total joint replacement (TJR). Due to an aging population and the constant rise in …

Background and Objectives: Despite the promise of phage therapy (PT), its efficacy in
prosthetic joint infection (PJI) management is unknown. Much of the current literature is …

There is a strong rationale for using phages in patients with bone and joint infections (BJIs).
Indeed, specific phages can infect and replicate in bacterial pathogens and have also …

Objectives Interest in phages as adjunctive therapy to treat difficult infections has grown in
the last decade. However, phage dosing and delivery for orthopedic infections have not …

The treatment of musculoskeletal infections (MSIs), including periprosthetic joint infection
(PJI) and fracture-related infection (FRI), is often complicated by biofilm-related challenges …

Prosthetic joint infection (PJI) is a devastating complication after a joint replacement. PJI and
its treatment have a high monetary cost, morbidity, and mortality. The lack of success treating …

Implant-associated infection (IAI) remains a significant issue in orthopaedic surgery.
Bacteriophages are naturally occurring viruses that kill bacteria. Bacteriophages are being …

Bacteriophage therapy is a promising treatment for periprosthetic joint infections (PJIs),
particularly given these agents have innate abilities to degrade the biofilm matrix and lyse …

Bacterial resistance to antibiotics has catalysed interest in alternative antimicrobial
strategies. Bacteriophages (phages) are viruses of bacteria with a long history of successful …