Previous studies have shown that epigenetic factors are involved in the occurrence and
development of rheumatoid arthritis (RA). However, the role of N 6-methyladenosine (m 6 A) …

Objective. Fibroblast-like synoviocytes (FLSs) are critical for promoting joint damage in
rheumatoid arthritis (RA). N6-methyladenosine (m6A) modification plays key roles in various …

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease. Recently, NLRP3
has been demonstrated to be closely related to RA. The objective of our research was to …

ALKBH5 (alkylation repair homolog protein 5), FTO (fat mass and obesity-associated
protein), and RNA N6-methyladenosine (m6A) demethylase, are essential for the m6A …

Synovial fibroblast hyperplasia, T‐cell hyperactivity, B‐cell overactivation, and the self‐
perpetuating interactions among these cell types are major characteristics of rheumatoid …

Rheumatoid arthritis (RA) is a systemic autoimmune disorder that manifests as chronic
inflammation and joint tissue destruction. However, the etiology and pathogenesis of RA …

Objectives Rheumatoid arthritis (RA) is a disease characterised by bone destruction and
systemic inflammation, and interleukin‐6 (IL‐6) is a therapeutic target for treating it. The …

Rheumatoid arthritis (RA) occurs in about 5 per 1,000 people and can lead to severe joint
damage and disability. However, the knowledge of pathogenesis and treatment for RA …

G-protein coupled receptor (GPCR) kinases (GRKs) and hypoxia-inducible factor-1α (HIF-
1α) play key roles in rheumatoid arthritis (RA). Several studies have demonstrated that HIF …

Although it has been proved that the epigenetic modification of DNA and histones is
involved in the pathogenesis of systemic lupus erythematosus (SLE), there is no study to …