Insomnia is a heritable, highly prevalent sleep disorder for which no sufficient treatment
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …

Insomnia is the second most prevalent mental disorder, with no sufficient treatment
available. Despite substantial heritability, insight into the associated genes and …

Persistent insomnia is among the most frequent complaints in general practice. To identify
genetic factors for insomnia complaints, we performed a genome-wide association study …

Insomnia is a worldwide problem with substantial deleterious health effects. Twin studies
have shown a heritable basis for various sleep-related traits, including insomnia, but robust …

This review summarizes current research on the genetics of insomnia, as genetic
contributions are thought to be important for insomnia etiology. We begin by providing an …

Chronic sleep disturbances, associated with cardiometabolic diseases, psychiatric disorders
and all-cause mortality,, affect 25–30% of adults worldwide. Although environmental factors …

Insomnia is a common disorder linked with adverse long-term medical and psychiatric
outcomes. The underlying pathophysiological processes and causal relationships of …

Several aspects of sleep behavior such as timing, duration and quality have been
demonstrated to be heritable. To identify common variants that influence sleep traits in the …

Excessive daytime sleepiness (EDS) affects 10–20% of the population and is associated
with substantial functional deficits. Here, we identify 42 loci for self-reported daytime …

Deciphering the genetic relationships between major depressive disorder (MDD) and
insomnia may facilitate understanding biological mechanisms as well as inform more …