The effects of dietary interventions on brain aging and neurological diseases

F Lobo, J Haase, S Brandhorst - Nutrients, 2022 - mdpi.com
Dietary interventions can ameliorate age-related neurological decline. Decades of research
of in vitro studies, animal models, and clinical trials support their ability and efficacy to …

Does diet have a role in the treatment of Alzheimer's disease?

M Thelen, HM Brown-Borg - Frontiers in aging neuroscience, 2020 - frontiersin.org
The aging process causes many changes to the brain and is a major risk factor for the
development of neurodegenerative diseases such as Alzheimer's Disease (AD). Despite an …

Caloric restriction and intermittent fasting: two potential diets for successful brain aging

B Martin, MP Mattson, S Maudsley - Ageing research reviews, 2006 - Elsevier
The vulnerability of the nervous system to advancing age is all too often manifest in
neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. In this review …

Diet and lifestyle impact the development and progression of Alzheimer's dementia

S Arora, JA Santiago, M Bernstein… - Frontiers in Nutrition, 2023 - frontiersin.org
Dementia is a growing public health concern, with an estimated prevalence of 57 million
adults worldwide. Alzheimer's disease (AD) accounts for 60–80% of the cases. Clinical trials …

Neuroprotective signaling and the aging brain: take away my food and let me run

MP Mattson - Brain research, 2000 - Elsevier
It is remarkable that neurons are able to survive and function for a century or more in many
persons that age successfully. A better understanding of the molecular signaling …

Nutrition and prevention of Alzheimer's dementia

A Swaminathan, GA Jicha - Frontiers in aging neuroscience, 2014 - frontiersin.org
A nutritional approach to prevent, slow, or halt the progression of disease is a promising
strategy that has been widely investigated. Much epidemiologic data suggests that …

Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms

MP Mattson, W Duan, Z Guo - Journal of neurochemistry, 2003 - Wiley Online Library
Although all cells in the body require energy to survive and function properly, excessive
calorie intake over long time periods can compromise cell function and promote disorders …

Nutrition, brain aging, and neurodegeneration

J Joseph, G Cole, E Head, D Ingram - Journal of Neuroscience, 2009 - Soc Neuroscience
The onset of age-related neurodegenerative diseases superimposed on a declining nervous
system could enhance the motor and cognitive behavioral deficits that normally occur in …

Effects of dietary restriction on neuroinflammation in neurodegenerative diseases

L Fontana, L Ghezzi, AH Cross, L Piccio - Journal of Experimental …, 2021 - rupress.org
Recent and accumulating work in experimental animal models and humans shows that diet
has a much more pervasive and prominent role than previously thought in modulating …

The impact of dietary energy intake on cognitive aging

MP Mattson - Frontiers in aging neuroscience, 2010 - frontiersin.org
Rodents that are insulin resistant and obese as the result of genetic factors, overeating
and/or a sedentary lifestyle, exhibit cognitive deficits that worsen with advancing age …