The immune system is a network of specialized cell types and tissues that communicates via
cytokines and direct contact, to orchestrate specific types of defensive responses. Until …

Vaccines represent a potent tool to prevent or contain infectious diseases with high
morbidity or mortality. However, despite their widespread use, we still have a limited …

Vaccination has been tremendously successful saving lives and preventing infections.
However, the development of vaccines against global pandemics such as HIV, malaria and …

In this issue of Immunity, a collection of detailed reviews summarizes needs, opportunities,
and roadblocks to the development of new vaccines, all in the context of our current …

Vaccines have drastically reduced the mortality and morbidity of many diseases. However,
vaccines have historically been developed empirically, and recent development of vaccines …

Immunomonitoring is the study of an individual's immune responses over the course of
vaccination or infection. In the infectious context, exploring the innate and adaptive immune …

Vaccines represent one of the greatest triumphs of modern medicine. Despite the common
origins of vaccinology and immunology more than 200 years ago, the two disciplines have …

Vaccines represent one of the major advances of modern medicine. Despite the many
successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” …

The science of immunology began in the 19th century. Louis Pasteur and Robert Koch
established that microorganisms were the actual cause of infectious diseases, which greatly …

At the current time, the field of vaccinology remains empirical in many respects. Vaccine
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …