Tightly orchestrated programmed cell death (PCD) signalling events occur during normal
neuronal development in a spatially and temporally restricted manner to establish the neural …

Rapid progress in understanding the molecular basis of neurodegeneration has been tightly
linked with recent discoveries in the field of programmed cell death (PCD). Analysis of PCD …

Molecular pathways of programmed cell death (PCD) are activated in various
neurodegenerative disorders including Parkinson's disease, amyotrophic lateral sclerosis …

There are common mechanisms shared by genetically or pathologically distinct
neurodegenerative diseases, such as excitotoxicity, mitochondrial deficits and oxidative …

Neuronal death is normal during nervous system development but is abnormal in brain and
spinal cord disease and injury. Apoptosis and necrosis are types of cell death. They are …

Synaptic degeneration and death of neurons in limbic and cortical brain regions are the
fundamental processes responsible for the manifestation of cognitive dysfunction and …

More than half of the initially-formed neurons are deleted in certain brain regions during
normal development. This process, whereby cells are discretely removed without interfering …

Apoptosis is an important process in the development of the nervous system. Typically,∼
50% of the neurons apoptose during neurogenesis before the nervous system matures …

Regulated cell death (RCD) is a ubiquitous process in living organisms that is essential for
tissue homeostasis or to restore biological balance under stress. Over the decades, various …

Programmed cell death (PCD) plays critical roles in development, homeostasis, and both
control and progression of a plethora of diseases, including cancer and neurodegenerative …